PURPOSE: To report the first case of sarcoid-related uveitis in a patient receiving adalimumab. DESIGN: Case report. METHODS: A 61-year-old woman with rheumatoid arthritis treated with adalimumab for 4 years presented with a 1-year history of bilateral panuveitis with venous vasculitis and peripheral multifocal choroiditis. A small papular lesion was found on her forehead, which upon biopsy showed noncaseating granulomas. No systemic involvement was observed. RESULTS: An ophtalmological and clinical improvement was seen after (TNF) antagonist withdrawal plus a course of prednisone. CONCLUSIONS: Ophthalmologists should know that a sarcoid-like granulomatosis can develop during TNFα blockade therapy.
PURPOSE: To report the first case of sarcoid-related uveitis in a patient receiving adalimumab. DESIGN: Case report. METHODS: A 61-year-old woman with rheumatoid arthritis treated with adalimumab for 4 years presented with a 1-year history of bilateral panuveitis with venous vasculitis and peripheral multifocal choroiditis. A small papular lesion was found on her forehead, which upon biopsy showed noncaseating granulomas. No systemic involvement was observed. RESULTS: An ophtalmological and clinical improvement was seen after (TNF) antagonist withdrawal plus a course of prednisone. CONCLUSIONS: Ophthalmologists should know that a sarcoid-like granulomatosis can develop during TNFα blockade therapy.
Authors: Carl Stanley Wilkins; Kristen Taylor Ashourian; Ethan Kyle Sobol; Matthew Fink; Brian Saltzman; Steven Teich Journal: J Curr Ophthalmol Date: 2021-07-05
Authors: Helio V Neves da Silva; John Placide; Anne Duong; Yasmyne Ronquillo; Shannon McCabe; Majid Moshirfar Journal: Ther Adv Ophthalmol Date: 2022-04-26