Literature DB >> 22015492

Case of isolated thrombocytopenia due to cobalamin deficiency.

Mesut Okur1, Aybars Ozkan, Cemalettin Gunes, Murat Kaya, Kenan Kocabay.   

Abstract

The most common form of isolated thrombocytopenia is idiopathic thrombocytopenic purpura (ITP) in childhood. Hence, pediatricians consider a possible diagnosis of ITP in patients with isolated thrombocytopenia who are admitted to hospital with complaints of skin findings such as petechiae, purpura, and ecchymosis. It is well known that cobalamin deficiency may also cause thrombocytopenia together with anemia and leukopenia in children. However, isolated thrombocytopenia due to cobalamin deficiency has rarely been reported in literature. In this case report, we present a 7-year-old female patient with isolated thrombocytopenia that was improved by cyanocobalamin therapy.

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Year:  2011        PMID: 22015492     DOI: 10.1007/s12185-011-0946-0

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  13 in total

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Authors:  S A Rasmussen; P M Fernhoff; K S Scanlon
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Review 2.  Immune thrombocytopenic purpura.

Authors:  Douglas B Cines; Victor S Blanchette
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3.  A child with vitamin B12 deficiency presenting with pancytopenia and hyperpigmentation.

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4.  Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.

Authors:  H Refsum; C S Yajnik; M Gadkari; J Schneede; S E Vollset; L Orning; A B Guttormsen; A Joglekar; M G Sayyad; A Ulvik; P M Ueland
Journal:  Am J Clin Nutr       Date:  2001-08       Impact factor: 7.045

5.  Amegakaryocytic thrombocytopenia of nutritional vitamin B12 deficiency.

Authors:  K Ghosh; R Sarode; N Varma; S Varma; G Garewal
Journal:  Trop Geogr Med       Date:  1988-04

6.  Clinical spectrum and diagnosis of cobalamin deficiency.

Authors:  S P Stabler; R H Allen; D G Savage; J Lindenbaum
Journal:  Blood       Date:  1990-09-01       Impact factor: 22.113

7.  Severe vitamin B-12 deficiency in a child mimicking thrombotic thrombocytopenic purpura.

Authors:  Andrea Dimond; James N George; Caroline Hastings
Journal:  Pediatr Blood Cancer       Date:  2009-03       Impact factor: 3.167

8.  Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies.

Authors:  D G Savage; J Lindenbaum; S P Stabler; R H Allen
Journal:  Am J Med       Date:  1994-03       Impact factor: 4.965

9.  Vitamin B-12 deficiency and malabsorption are highly prevalent in rural Mexican communities.

Authors:  L H Allen; J L Rosado; J E Casterline; H Martinez; P Lopez; E Muñoz; A K Black
Journal:  Am J Clin Nutr       Date:  1995-11       Impact factor: 7.045

Review 10.  Vitamin B12 (cobalamin) deficiency in elderly patients.

Authors:  Emmanuel Andrès; Noureddine Henoun Loukili; Esther Noel; Georges Kaltenbach; Maher Ben Abdelgheni; Anne Elisabeth Perrin; Marie Noblet-Dick; Frédéric Maloisel; Jean-Louis Schlienger; Jean-Frédéric Blicklé
Journal:  CMAJ       Date:  2004-08-03       Impact factor: 8.262

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