Literature DB >> 22014123

So what do we call GPR18 now?

S P H Alexander1.   

Abstract

The further characterization of the orphan GPCR GPR18 conducted by McHugh et al. in this issue of the British Journal of Pharmacology has generated a pharmacological profile that raises some interesting questions about the nomenclature of this receptor and may also prompt some questions about the pharmacological definition of the classical cannabinoid receptors, CB(1) and CB(2) . LINKED ARTICLES This article is a commentary on McHugh et al., pp. 2414-2424 of this issue and is part of a themed section on Cannabinoids in Biology and Medicine. To view McHugh et al. visit http://dx.doi.org/10.1111/j.1476-5381.2011.01497.x. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2012.165.issue-8. To view Part I of Cannabinoids in Biology and Medicine visit http://dx.doi.org/10.1111/bph.2011.163.issue-7.
© 2011 The Author. British Journal of Pharmacology © 2011 The British Pharmacological Society.

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Year:  2012        PMID： 22014123      PMCID： PMC3423231          DOI： 10.1111/j.1476-5381.2011.01731.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  18 in total

1.  Cloning and chromosomal localization of a gene (GPR18) encoding a novel seven transmembrane receptor highly expressed in spleen and testis.

Authors:  I Gantz; A Muraoka; Y K Yang; L C Samuelson; E M Zimmerman; H Cook; T Yamada
Journal:  Genomics       Date:  1997-06-15       Impact factor: 5.736

2.  N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a.

Authors:  Amy L Wiles; Rhonda-Jo Pearlman; Mari Rosvall; Karin R Aubrey; Robert J Vandenberg
Journal:  J Neurochem       Date:  2006-08-08       Impact factor: 5.372

3.  Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor.

Authors:  T Sheskin; L Hanus; J Slager; Z Vogel; R Mechoulam
Journal:  J Med Chem       Date:  1997-02-28       Impact factor: 7.446

4.  Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

Authors:  S M Huang; T Bisogno; T J Petros; S Y Chang; P A Zavitsanos; R E Zipkin; R Sivakumar; A Coop; D Y Maeda; L De Petrocellis; S Burstein; V Di Marzo; J M Walker
Journal:  J Biol Chem       Date:  2001-08-22       Impact factor: 5.157

5.  Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol.

Authors:  Nazdar Ghafouri; Gunnar Tiger; Raj K Razdan; Anu Mahadevan; Roger G Pertwee; Billy R Martin; Christopher J Fowler
Journal:  Br J Pharmacol       Date:  2004-10-18       Impact factor: 8.739

6.  Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18.

Authors:  Masashi Kohno; Hitoshi Hasegawa; Atsushi Inoue; Masatake Muraoka; Tatsuhiko Miyazaki; Keizo Oka; Masaki Yasukawa
Journal:  Biochem Biophys Res Commun       Date:  2006-07-10       Impact factor: 3.575

7.  Cytochrome c catalyzes the in vitro synthesis of arachidonoyl glycine.

Authors:  Jeffrey M McCue; William J Driscoll; Gregory P Mueller
Journal:  Biochem Biophys Res Commun       Date:  2007-11-05       Impact factor: 3.575

8.  Selective oxygenation of N-arachidonylglycine by cyclooxygenase-2.

Authors:  Jeffery J Prusakiewicz; Philip J Kingsley; Kevin R Kozak; Lawrence J Marnett
Journal:  Biochem Biophys Res Commun       Date:  2002-08-23       Impact factor: 3.575

9.  Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92.

Authors:  Da Young Oh; Jung Min Yoon; Mi Jin Moon; Jong-Ik Hwang; Han Choe; Ju Yeon Lee; Jae Il Kim; Sunoh Kim; Hyewhon Rhim; David K O'Dell; J Michael Walker; Heung Sik Na; Min Goo Lee; Hyuk Bang Kwon; Kyungjin Kim; Jae Young Seong
Journal:  J Biol Chem       Date:  2008-05-22       Impact factor: 5.157

10.  Sex and hormonal cycle differences in rat brain levels of pain-related cannabimimetic lipid mediators.

Authors:  Heather B Bradshaw; Neta Rimmerman; Jocelyn F Krey; J Michael Walker
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2006-03-23       Impact factor: 3.619
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  12 in total

Review 1.  GPR18 in microglia: implications for the CNS and endocannabinoid system signalling.

Authors:  D McHugh
Journal:  Br J Pharmacol       Date:  2012-12       Impact factor: 8.739

2.  2012 cannabinoid themed section.

Authors:  Stephen P H Alexander
Journal:  Br J Pharmacol       Date:  2012-12       Impact factor: 8.739

Review 3.  Endothelial atypical cannabinoid receptor: do we have enough evidence?

Authors:  Alexander I Bondarenko
Journal:  Br J Pharmacol       Date:  2014-12       Impact factor: 8.739

4.  The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors.

Authors:  Stephen P H Alexander; Helen E Benson; Elena Faccenda; Adam J Pawson; Joanna L Sharman; Michael Spedding; John A Peters; Anthony J Harmar
Journal:  Br J Pharmacol       Date:  2013-12       Impact factor: 8.739

5.  Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats.

Authors:  Anusha Penumarti; Abdel A Abdel-Rahman
Journal:  J Pharmacol Exp Ther       Date:  2014-08-06       Impact factor: 4.030

6.  The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonists.

Authors:  Alexander Fuchs; Viktor Rempel; Christa E Müller
Journal:  PLoS One       Date:  2013-10-30       Impact factor: 3.240

7.  Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats.

Authors:  Gang Zuo; Dongping Zhang; Rutao Mu; Haitao Shen; Xiang Li; Zhong Wang; Haiying Li; Gang Chen
Journal:  Mol Brain       Date:  2018-02-13       Impact factor: 4.041

8.  Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.

Authors:  Madhur P Motwani; Romain A Colas; Marc J George; Julia D Flint; Jesmond Dalli; Angela Richard-Loendt; Roel Ph De Maeyer; Charles N Serhan; Derek W Gilroy
Journal:  JCI Insight       Date:  2018-03-22

9.  N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.

Authors:  Alexander I Bondarenko; Konstantin Drachuk; Olga Panasiuk; Vadim Sagach; Andras T Deak; Roland Malli; Wolfgang F Graier
Journal:  Br J Pharmacol       Date:  2013-06       Impact factor: 8.739

10.  CB2 receptor activation inhibits melanoma cell transmigration through the blood-brain barrier.

Authors:  János Haskó; Csilla Fazakas; Judit Molnár; Ádám Nyúl-Tóth; Hildegard Herman; Anca Hermenean; Imola Wilhelm; Yuri Persidsky; István A Krizbai
Journal:  Int J Mol Sci       Date:  2014-05-08       Impact factor: 5.923
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