Literature DB >> 22013190

Why is chromosome segregation error in oocytes increased with maternal aging?

Zhen-Bo Wang1, Heide Schatten, Qing-Yuan Sun.   

Abstract

It is well documented that female fertility is decreased with advanced maternal age due to chromosome abnormality in oocytes. Increased chromosome missegregation is mainly caused by centromeric cohesion reduction. Other factors such as weakened homologous recombination, improper spindle organization, spindle assembly checkpoint (SAC) malfunction, chromatin epigenetic changes, and extra-oocyte factors may also cause chromosome errors.

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Year:  2011        PMID： 22013190     DOI： 10.1152/physiol.00020.2011

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  12 in total

1.  Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.

Authors:  Yan Yun; Janet E Holt; Simon I R Lane; Eileen A McLaughlin; Julie A Merriman; Keith T Jones
Journal:  Cell Cycle       Date:  2014-04-23       Impact factor: 4.534

Review 2.  Functions and dysfunctions of the mammalian centrosome in health, disorders, disease, and aging.

Authors:  Heide Schatten; Qing-Yuan Sun
Journal:  Histochem Cell Biol       Date:  2018-07-30       Impact factor: 4.304

3.  Predictive value of spindle retardance in embryo implantation rate.

Authors:  Sabela García-Oro; María Isabel Rey; Marta Rodríguez; Ángel Durán; Roque Devesa; Diana Valverde
Journal:  J Assist Reprod Genet       Date:  2017-03-09       Impact factor: 3.412

4.  Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey.

Authors:  Dongdong Zhang; Xiaoqian Zhang; Ming Zeng; Jihong Yuan; Mengyuan Liu; Yu Yin; Xueqing Wu; David L Keefe; Lin Liu
Journal:  J Assist Reprod Genet       Date:  2015-05-10       Impact factor: 3.412

5.  Lack of response to unaligned chromosomes in mammalian female gametes.

Authors:  Jaroslava Sebestova; Anna Danylevska; Lucia Novakova; Michal Kubelka; Martin Anger
Journal:  Cell Cycle       Date:  2012-08-08       Impact factor: 4.534

6.  The prevalence of chromosomal deletions relating to developmental delay and/or intellectual disability in human euploid blastocysts.

Authors:  Wenyin He; Xiaofang Sun; Lian Liu; Man Li; Hua Jin; Wei-Hua Wang
Journal:  PLoS One       Date:  2014-01-07       Impact factor: 3.240

7.  Arrested human embryos are more likely to have abnormal chromosomes than developing embryos from women of advanced maternal age.

Authors:  Shu-Tao Qi; Li-Feng Liang; Ye-Xing Xian; Jian-Qiao Liu; Weihua Wang
Journal:  J Ovarian Res       Date:  2014-06-13       Impact factor: 4.234

Review 8.  The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility.

Authors:  Heide Schatten; Qing-Yuan Sun; Randall Prather
Journal:  Reprod Biol Endocrinol       Date:  2014-11-24       Impact factor: 5.211

9.  Transfer of autologous mitochondria from adipose tissue-derived stem cells rescues oocyte quality and infertility in aged mice.

Authors:  Zhen-Bo Wang; Jian-Xiu Hao; Tie-Gang Meng; Lei Guo; Ming-Zhe Dong; Li-Hua Fan; Ying-Chun Ouyang; Guopeng Wang; Qing-Yuan Sun; Xiang-Hong Ou; Yuan-Qing Yao
Journal:  Aging (Albany NY)       Date:  2017-12-27       Impact factor: 5.682

10.  Nicotinamide Supplementation Improves Oocyte Quality and Offspring Development by Modulating Mitochondrial Function in an Aged Caenorhabditis elegans Model.

Authors:  Hyemin Min; Mijin Lee; Kyoung Sang Cho; Hyunjung Jade Lim; Yhong-Hee Shim
Journal:  Antioxidants (Basel)       Date:  2021-03-26
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