| Literature DB >> 22012008 |
Yuan Lu1, Guoya Ling, Chenyi Qiang, Qinshou Ming, Cong Wu, Ke Wang, Zouxiao Ying.
Abstract
We undertook a bivariate meta-analysis to assess the overall accuracy of respiratory specimen PCR assays for diagnosing Pneumocystis pneumonia. The summary sensitivity and specificity were 0.99 (95% confidence interval, 0.96 to 1.00) and 0.90 (0.87 to 0.93). Subgroup analyses showed that quantitative PCR analysis and the major surface glycoprotein gene target had the highest specificity value (0.93). Respiratory specimen PCR results are sufficient to confirm or exclude the disease for at-risk patients suspected of having Pneumocystis pneumonia.Entities:
Mesh:
Year: 2011 PMID: 22012008 PMCID: PMC3232995 DOI: 10.1128/JCM.06066-11
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948