| Literature DB >> 22008460 |
Alideertu Dong1, Shi Lan, Jinfeng Huang, Tao Wang, Tianyi Zhao, Linghan Xiao, Weiwei Wang, Xin Zheng, Fengqi Liu, Ge Gao, Yuxin Chen.
Abstract
Magnetic/antibacterial bifunctional nanoparticles were fabricated through the immobilization of antibacterial N-halamine on silica-coated Fe(3)O(4)-decorated poly(styrene-co-acrylate acid) (PSA) nanoparticles. The samples were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectra (XPS), X-ray diffraction (XRD), energy-dispersive X-ray spectrometry (EDX), Fourier transform infrared (FTIR), and thermogravimetric analysis (TGA). The N-halamine was developed from the precursor 5,5-dimethylhydantoin (DMH) by chlorination treatment, and experimental results showed that the loading amount of DMH on the silica-coated Fe(3)O(4)-decorated poly(styrene-co-acrylate acid) nanoparticles was adjustable. The as-synthesized nanoparticles exhibited superparamagnetic behavior and had a saturation magnetization of 18.93 emu g(-1). Antibacterial tests showed that the resultant nanoparticles displayed enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria compared with their bulk counterparts.Entities:
Mesh：
Substances：
Year: 2011 PMID： 22008460 DOI： 10.1021/am200864p
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN： 1944-8244 Impact factor: 9.229