Literature DB >> 22007699

How psoriasis patients perceive, obtain, and use biologic agents: Survey from an academic medical center.

Faranak Kamangar1, Leah Isip, Tina Bhutani, Madison Dennis, Misha M Heller, Eric S Lee, Hong Nie, Wilson Liao.   

Abstract

The availability of new biologic agents for the treatment of psoriasis provides hope for improved quality of life outcomes. However, the way patients come to use biologics, the potential barriers they encounter, and their attitudes towards using these medications are still not well studied. Here, we conducted a survey of 106 psoriasis patients at an academic medical center to discern patient attitudes towards biologics. We found that most patients learn of biologics through their physician and perform follow-up research using the Internet. Most patients did not find it difficult to make the decision to start a biologic. Difficulty in obtaining biologics was associated with age less than 55 (p = 0.01), lower income level (p = 0.007), and lack of insurance (p = 0.04). Patients were found to have high satisfaction and compliance rates on biologics. Of patients who missed a dose of their biologic, this was mainly due to logistical reasons such as not having the medication or forgetting to take it, rather than being depressed or overwhelmed. Patients with lower income levels had increased cut backs in personal expenses due to co-payments (p = 0.001). Among respondents, the mean annual out-of-pocket expense for a biologic was $557.12 per year, with a range of $0-7000.

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Year:  2011        PMID: 22007699      PMCID: PMC3679890          DOI: 10.3109/09546634.2011.631979

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  16 in total

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Authors:  M A Gupta; A K Gupta
Journal:  Br J Dermatol       Date:  1998-11       Impact factor: 9.302

Review 2.  Patient satisfaction with psoriasis therapies: an update and introduction to biologic therapy.

Authors:  Andrew Y Finlay; Jean-Paul Ortonne
Journal:  J Cutan Med Surg       Date:  2004 Sep-Oct       Impact factor: 2.092

Review 3.  The effect of psoriasis on patients' quality of life and improvements associated with alefacept therapy.

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Journal:  J Cutan Med Surg       Date:  2004-12       Impact factor: 2.092

4.  The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation patient-membership survey.

Authors:  G Krueger; J Koo; M Lebwohl; A Menter; R S Stern; T Rolstad
Journal:  Arch Dermatol       Date:  2001-03

Review 5.  The impact of biologics on the quality of life of psoriasis patients and the economics of psoriasis care.

Authors:  Kevin R Stein; Daniel J Pearce; Steven R Feldman
Journal:  Semin Cutan Med Surg       Date:  2005-03

6.  The psychosocial impact of psoriasis: physical severity, quality of life, and stigmatization.

Authors:  S B Perrott; A H Murray; J Lowe; C M Mathieson
Journal:  Physiol Behav       Date:  2000-09-15

Review 7.  The Dermatology Life Quality Index: assessing the efficacy of biological therapies for psoriasis.

Authors:  R P Katugampola; V J Lewis; A Y Finlay
Journal:  Br J Dermatol       Date:  2007-03-28       Impact factor: 9.302

8.  The economic impact of high-need psoriasis in daily clinical practice before and after the introduction of biologics.

Authors:  R J B Driessen; L A Bisschops; E M M Adang; A W Evers; P C M Van De Kerkhof; E M G J De Jong
Journal:  Br J Dermatol       Date:  2010-02-15       Impact factor: 9.302

9.  The negative impact of psoriasis on the workplace.

Authors:  Daniel J Pearce; Saurabh Singh; Rajesh Balkrishnan; Amit Kulkarni; Alan B Fleischer; Steven R Feldman
Journal:  J Dermatolog Treat       Date:  2006       Impact factor: 3.359

10.  Use of biological agents in patients with moderate to severe psoriasis: a cohort-based perspective.

Authors:  María Jones-Caballero; Jane Unaeze; Pablo F Peñas; Robert S Stern
Journal:  Arch Dermatol       Date:  2007-07
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  8 in total

Review 1.  Evaluating Risk Tolerance from a Systematic Review of Preferences: The Case of Patients with Psoriasis.

Authors:  Juan Marcos Gonzalez
Journal:  Patient       Date:  2018-06       Impact factor: 3.883

Review 2.  A patient-centred approach to biological treatment decision making for psoriasis: an expert consensus.

Authors:  R Strohal; J C Prinz; G Girolomoni; A Nast
Journal:  J Eur Acad Dermatol Venereol       Date:  2015-09-14       Impact factor: 6.166

3.  Impact of Treatment-Related Beliefs on Medication Adherence in Immune-Mediated Inflammatory Diseases: Results of the Global ALIGN Study.

Authors:  Pierre Michetti; John Weinman; Ulrich Mrowietz; Josef Smolen; Laurent Peyrin-Biroulet; Edouard Louis; Dieter Schremmer; Namita Tundia; Pascal Nurwakagari; Nicole Selenko-Gebauer
Journal:  Adv Ther       Date:  2016-11-16       Impact factor: 3.845

Review 4.  Medication adherence and persistence in patients with rheumatoid arthritis, psoriasis, and psoriatic arthritis: a systematic literature review.

Authors:  Mwangi J Murage; Vanita Tongbram; Steven R Feldman; William N Malatestinic; Cynthia J Larmore; Talia M Muram; Russel T Burge; Charles Bay; Nicole Johnson; Sarah Clifford; Andre B Araujo
Journal:  Patient Prefer Adherence       Date:  2018-08-21       Impact factor: 2.711

5.  Psoriasis in the US Medicare Population: Prevalence, Treatment, and Factors Associated with Biologic Use.

Authors:  Junko Takeshita; Joel M Gelfand; Penxiang Li; Lionel Pinto; Xinyan Yu; Preethi Rao; Hema N Viswanathan; Jalpa A Doshi
Journal:  J Invest Dermatol       Date:  2015-07-27       Impact factor: 8.551

Review 6.  An evolution in switching therapy for psoriasis patients who fail to meet treatment goals.

Authors:  Francisco Kerdel; Martin Zaiac
Journal:  Dermatol Ther       Date:  2015-08-10       Impact factor: 2.851

Review 7.  Psoriasis in childhood: effective strategies to improve treatment adherence.

Authors:  Kara N Shah; Sandra Cortina; Michelle M Ernst; Jessica C Kichler
Journal:  Psoriasis (Auckl)       Date:  2015-03-16

8.  Highlights of the updated Dutch evidence- and consensus-based guideline on psoriasis 2017.

Authors:  G E van der Kraaij; D M W Balak; C I Busard; O D van Cranenburgh; Y Chung; R J B Driessen; M de Groot; E M G J de Jong; P M J H Kemperman; W J A de Kort; S A Karsch; A Lamberts; L L A Lecluse; P P M van Lümig; S P Menting; E P Prens; J M P A van den Reek; M M B Seyger; H B Thio; W R Veldkamp; M Wakkee; A Nast; A Jacobs; S Rosumeck; P I Spuls Chair
Journal:  Br J Dermatol       Date:  2019-01       Impact factor: 9.302

  8 in total

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