| Literature DB >> 22007554 |
Xiaofei Wang1, Baoxia Zang, Wei Wu, Jing Tong, Ming Jin.
Abstract
To observe the protective effect of hydroxyl safflor yellow A (HSYA) on endothelial cell (EC). It has been observed by RT-PCR that HSYA can inhibit the elevation of TNF-alpha, IL-6, ICAM-1 and VCAM-1 mRNA level induced by LPS. The result of immunofluorescence test suggested that HSYA can alleviate p65 subgroup of NF-kappaB nuclear translocation. The experiment on EA-HY926 cell line proved that HSYA can protect EC against inflammation injury.Entities:
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Year: 2011 PMID： 22007554
Source DB: PubMed Journal: Zhongguo Zhong Yao Za Zhi ISSN： 1001-5302