Literature DB >> 2200684

Improvement of drug absorption through enhancers.

A G de Boer1, E J van Hoogdalem, D D Breimer.   

Abstract

The application of enhancers for improvement of drug absorption via the nasal, transdermal and rectal route are outlined. The importance of the relation between the time course of the enhancing effect and the desired plasma - concentration - time profile of the drug is stressed as well as the need to pay more attention to the safety aspects of absorption enhancers.

Mesh：

Year:  1990        PMID： 2200684     DOI： 10.1007/BF03190198

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


  12 in total

1.  Transdermal iontophoretic drug delivery: mechanistic analysis and application to polypeptide delivery.

Authors:  V Srinivasan; W I Higuchi; S M Sims; A H Ghanem; C R Behl
Journal:  J Pharm Sci       Date:  1989-05       Impact factor: 3.534

2.  Rectal absorption enhancement of cefoxitin and desglycinamide arginine vasopressin by sodium tauro-24,25-dihydrofusidate in conscious rats.

Authors:  E J van Hoogdalem; C D Heijligers-Feijen; R A Mathôt; A T Wackwitz; J B van Bree; J C Verhoef; A G de Boer; D D Breimer
Journal:  J Pharmacol Exp Ther       Date:  1989-11       Impact factor: 4.030

Review 3.  Enzymatic barriers to peptide and protein absorption.

Authors:  V H Lee
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  1988       Impact factor: 4.889

Review 4.  The influence of drugs on nasal ciliary movement.

Authors:  W A Hermens; F W Merkus
Journal:  Pharm Res       Date:  1987-12       Impact factor: 4.200

Review 5.  Intestinal drug absorption enhancement: an overview.

Authors:  E J van Hoogdalem; A G de Boer; D D Breimer
Journal:  Pharmacol Ther       Date:  1989       Impact factor: 12.310

Review 6.  Controlled topical delivery of drugs for systemic action.

Authors:  J E Shaw; S K Chandrasekaran
Journal:  Drug Metab Rev       Date:  1978       Impact factor: 4.518

7.  Uptake and fate of absorbed amino acids and peptides in the mammalian intestine.

Authors:  D H Alpers
Journal:  Fed Proc       Date:  1986-07

Review 8.  Gastrointestinal absorption of intact proteins.

Authors:  M L Gardner
Journal:  Annu Rev Nutr       Date:  1988       Impact factor: 11.848

Review 9.  Rectal drug administration: clinical pharmacokinetic considerations.

Authors:  A G de Boer; F Moolenaar; L G de Leede; D D Breimer
Journal:  Clin Pharmacokinet       Date:  1982 Jul-Aug       Impact factor: 6.447

10.  Rate-controlled absorption enhancement of rectally administered cefazolin in rats by a glyceride mixture (MGK).

Authors:  E J van Hoogdalem; A M Stijnen; A G de Boer; D D Breimer
Journal:  J Pharm Pharmacol       Date:  1988-05       Impact factor: 3.765
View more
  1 in total

Review 1.  The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications.

Authors:  V Meunier; M Bourrié; Y Berger; G Fabre
Journal:  Cell Biol Toxicol       Date:  1995-08       Impact factor: 6.691
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.