Literature DB >> 22006435

The role of preoperative neck ultrasounds to assess lymph nodes in patients with suspicious or indeterminate thyroid nodules.

Rashmi Roy1, Guennadi Kouniavsky, Raghunandan Venkat, Erin A Felger, Zita Shiue, Eric Schneider, Martha A Zeiger.   

Abstract

BACKGROUND AND OBJECTIVES: Currently there are no recommendations for obtaining a preoperative neck ultrasound for patients with suspicious or indeterminate thyroid nodules. Because a preoperative surgical ultrasound can detect suspicious lymph nodes that could result in ultimately altering surgical management, we chose to study which variables were predictive of this change.
METHODS: Medical records of 173 patients who presented between January 2006 and December 2010 with suspicious or indeterminate thyroid cytology were retrospectively reviewed. Clinicopathological variables were analyzed to determine factors predictive of malignancy and a change in operative approach.
RESULTS: One hundred thirty-four of 173 patients were evaluable. Seventeen of 134 (12.6%) of the preoperative ultrasounds were suspicious. Seven of 134 (5.2%) patients underwent a formal lymph node dissection based on ultrasound findings. Size of tumor, Bethesda FNAB category, and male gender were associated with malignancy while thyroid nodule microcalcifications and category of FNAB were associated with performing lymph node dissections.
CONCLUSION: Thyroid nodule microcalcifications on ultrasound and category of FNAB appear to be the best predictors of metastatic disease. Because the surgical approach was altered in only a few patients, further analysis is needed to delineate whether performing cervical ultrasound for suspicious/indeterminate nodules is cost effective.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 22006435      PMCID: PMC3715078          DOI: 10.1002/jso.22115

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  37 in total

1.  The predictive value of ultrasound findings in the management of thyroid nodules.

Authors:  C Cappelli; M Castellano; I Pirola; D Cumetti; B Agosti; E Gandossi; E Agabiti Rosei
Journal:  QJM       Date:  2006-12-17

2.  Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.

Authors:  David S Cooper; Gerard M Doherty; Bryan R Haugen; Bryan R Hauger; Richard T Kloos; Stephanie L Lee; Susan J Mandel; Ernest L Mazzaferri; Bryan McIver; Furio Pacini; Martin Schlumberger; Steven I Sherman; David L Steward; R Michael Tuttle
Journal:  Thyroid       Date:  2009-11       Impact factor: 6.568

3.  Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer.

Authors:  Nephtali R Gomez; Guennadi Kouniavsky; Hua-Ling Tsai; Helina Somervell; Sara I Pai; Ralph P Tufano; Christopher Umbricht; Jeanne Kowalski; Alan P B Dackiw; Martha A Zeiger
Journal:  J Surg Oncol       Date:  2011-07-08       Impact factor: 3.454

4.  Value of preoperative ultrasonography in the surgical management of initial and reoperative papillary thyroid cancer.

Authors:  John M Stulak; Clive S Grant; David R Farley; Geoffrey B Thompson; Jon A van Heerden; Ian D Hay; Carl C Reading; J William Charboneau
Journal:  Arch Surg       Date:  2006-05

5.  Ultrasonographic differentiation of benign from malignant neck lymphadenopathy in thyroid cancer.

Authors:  Sanja Kusacic Kuna; Irena Bracic; Vanja Tesic; Krunoslav Kuna; Gordana Horvatic Herceg; Damir Dodig
Journal:  J Ultrasound Med       Date:  2006-12       Impact factor: 2.153

6.  Clinical features associated with an increased risk of thyroid malignancy in patients with follicular neoplasia by fine-needle aspiration.

Authors:  R M Tuttle; H Lemar; H B Burch
Journal:  Thyroid       Date:  1998-05       Impact factor: 6.568

7.  Ultrasonography-guided fine-needle aspiration of thyroid incidentaloma: correlation with pathological findings.

Authors:  Il Seong Nam-Goong; Ha Young Kim; Gyungyub Gong; Ho Kyu Lee; Suck Joon Hong; Won Bae Kim; Young Kee Shong
Journal:  Clin Endocrinol (Oxf)       Date:  2004-01       Impact factor: 3.478

Review 8.  Thyroid cancer nodal metastases: biologic significance and therapeutic considerations.

Authors:  S K Grebe; I D Hay
Journal:  Surg Oncol Clin N Am       Date:  1996-01       Impact factor: 3.495

9.  The National Cancer Institute Thyroid fine needle aspiration state of the science conference: a summation.

Authors:  Zubair W Baloch; Edmund S Cibas; Douglas P Clark; Lester J Layfield; Britt-Marie Ljung; Martha Bishop Pitman; Andrea Abati
Journal:  Cytojournal       Date:  2008-04-07       Impact factor: 2.091

10.  Evaluating the degree of conformity of papillary carcinoma and follicular carcinoma to the reported ultrasonographic findings of malignant thyroid tumor.

Authors:  Su-kyoung Jeh; So Lyung Jung; Bum Soo Kim; Yoen Soo Lee
Journal:  Korean J Radiol       Date:  2007 May-Jun       Impact factor: 3.500

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  4 in total

1.  Appropriate and accurate diagnosis of thyroid nodules: a review of thyroid fine-needle aspiration.

Authors:  Catherine Hambleton; Emad Kandil
Journal:  Int J Clin Exp Med       Date:  2013-06-26

2.  GAUGING THE EXTENT OF THYROIDECTOMY FOR INDETERMINATE THYROID NODULES: AN ONCOLOGIC PERSPECTIVE.

Authors:  David F Schneider; Linda M Cherney Stafford; Nicole Brys; Caprice C Greenberg; Courtney J Balentine; Dawn M Elfenbein; Susan C Pitt
Journal:  Endocr Pract       Date:  2017-01-17       Impact factor: 3.443

3.  American Thyroid Association statement on preoperative imaging for thyroid cancer surgery.

Authors:  Michael W Yeh; Andrew J Bauer; Victor A Bernet; Robert L Ferris; Laurie A Loevner; Susan J Mandel; Lisa A Orloff; Gregory W Randolph; David L Steward
Journal:  Thyroid       Date:  2015-01       Impact factor: 6.568

4.  All thyroid ultrasound evaluations are not equal: sonographers specialized in thyroid cancer correctly label clinical N0 disease in well differentiated thyroid cancer.

Authors:  Sarah C Oltmann; David F Schneider; Herbert Chen; Rebecca S Sippel
Journal:  Ann Surg Oncol       Date:  2014-09-19       Impact factor: 5.344

  4 in total

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