Literature DB >> 22005903

Holford NHG and Sheiner LB "Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models", Clin Pharmacokin 6:429-453 (1981)-The Backstory.

Nick Holford1.   

Abstract

Mesh：

Year:  2011        PMID： 22005903      PMCID： PMC3231857          DOI： 10.1208/s12248-011-9306-5

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


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  13 in total

1.  Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments.

Authors:  Nicholas H G Holford; Phylinda L S Chan; John G Nutt; Karl Kieburtz; Ira Shoulson
Journal:  J Pharmacokinet Pharmacodyn       Date:  2006-04-20       Impact factor: 2.745

2.  Relationship between the pharmacokinetics and pharmacodynamics of procainamide.

Authors:  R L Galeazzi; L Z Benet; L B Sheiner
Journal:  Clin Pharmacol Ther       Date:  1976-09       Impact factor: 6.875

3.  Computer-aided long-term anticoagulation therapy.

Authors:  L B Sheiner
Journal:  Comput Biomed Res       Date:  1969-12

4.  Kinetics of interaction between drugs and biological systems.

Authors:  G Segre
Journal:  Farmaco Sci       Date:  1968-10

Review 5.  Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models.

Authors:  N H Holford; L B Sheiner
Journal:  Clin Pharmacokinet       Date:  1981 Nov-Dec       Impact factor: 6.447

Review 6.  Pharmacokinetic and pharmacodynamic modeling in vivo.

Authors:  N H Holford; L B Sheiner
Journal:  Crit Rev Bioeng       Date:  1981

7.  Quantitative analysis of the disopyramide concentration-effect relationship.

Authors:  B Whiting; N H Holford; L B Sheiner
Journal:  Br J Clin Pharmacol       Date:  1980-01       Impact factor: 4.335

8.  Discrimination of three types of opioid binding sites in rat brain in vivo.

Authors:  J S Rosenbaum; N H Holford; M L Richards; R A Aman; W Sadée
Journal:  Mol Pharmacol       Date:  1984-03       Impact factor: 4.436

9.  Some quantitative uses of drug antagonists.

Authors:  O ARUNLAKSHANA; H O SCHILD
Journal:  Br J Pharmacol Chemother       Date:  1959-03

10.  Methodologic aspects of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine.

Authors:  N H Holford; K E Peace
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205
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  8 in total

1.  Target concentration intervention: beyond Y2K.

Authors:  N H Holford
Journal:  Br J Clin Pharmacol       Date:  1999-07       Impact factor: 4.335

2.  Pharmacodynamics of methylprednisolone phosphate after single intravenous administration to healthy volunteers.

Authors:  H Derendorf; H Möllmann; M Krieg; S Tunn; C Möllmann; J Barth; H J Röthig
Journal:  Pharm Res       Date:  1991-02       Impact factor: 4.200

Review 3.  Characteristics of indirect pharmacodynamic models and applications to clinical drug responses.

Authors:  A Sharma; W J Jusko
Journal:  Br J Clin Pharmacol       Date:  1998-03       Impact factor: 4.335

4.  Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships.

Authors:  Christopher Louizos; Jaime A Yáñez; M Laird Forrest; Neal M Davies
Journal:  J Pharm Pharm Sci       Date:  2014       Impact factor: 2.327

Review 5.  Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges.

Authors:  Kashyap Patel; Julie A Simpson; Kevin T Batty; Sophie Zaloumis; Carl M Kirkpatrick
Journal:  Br J Clin Pharmacol       Date:  2015-01       Impact factor: 4.335

6.  Pharmacodynamic models for the cardiovascular effects of moxonidine in patients with congestive heart failure.

Authors:  L Brynne; J L McNay; H G Schaefer; K Swedberg; C G Wiltse; M O Karlsson
Journal:  Br J Clin Pharmacol       Date:  2001-01       Impact factor: 4.335

7.  Verapamil disposition and cardiovascular effects in elderly patients after single intravenous and oral doses.

Authors:  L Carosella; P Menichelli; M Alimenti; G Zuccala; A Gemma; A Cocchi; P U Carbonin
Journal:  Cardiovasc Drugs Ther       Date:  1989-06       Impact factor: 3.727

8.  Influence of input rates on (+/-)-isradipine haemodynamics and concentration-effect relationship in healthy volunteers.

Authors:  V Carrara; H Porchet; P Dayer
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953
  8 in total

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