Liang-yun Ma1, Ze-fei Liao, Geng-jie Wang. 1. Department of Thoracic Surgery, PLA 180 Hospital Quanzhou City of Fujian Province, Quanzhou, Fujian, China.
Abstract
OBJECTIVE: To identify risk factors for post-surgical pulmonary complications in patients with mechanical ventilation for respiratory failure and pneumonia after esophagectomy in order to guide the development of individualized treatment-plan for high risk patients. METHODS: Clinical data from 82 patients received esophagectomy for cancer during May 2008 to June 2010 were analyzed retrospectively using Logistic regression for risk factors associated with the development of post-surgical pulmonary complication. RESULTS: Post-surgical pulmonary complications was found in 12 out of the 82 patients studied, and it was the primarily death cause for one of them. Multivariate Logistic analysis identified advanced age[odds ratio (OR) = 1.28, 95% confidence interval (95% CI ) 1.05-1.62, P = 0.03], impaired pulmonary function [forced expiratory volume in one second (FEV1) OR = 1.20, 95% CI 1.08-1.39, P = 0.02] and longer operation duration (OR = 1.68, 95% CI 1.37-2.11, P = 0.003) as risk factors. CONCLUSION: Advanced age and impaired lung function may be significant risk factors for pulmonary complications after esophagectomy. It is helpful to evaluate the risk of such complications by referring to these indexes before the surgery, and design individualized treatment-plan for patients at high risk.
OBJECTIVE: To identify risk factors for post-surgical pulmonary complications in patients with mechanical ventilation for respiratory failure and pneumonia after esophagectomy in order to guide the development of individualized treatment-plan for high risk patients. METHODS: Clinical data from 82 patients received esophagectomy for cancer during May 2008 to June 2010 were analyzed retrospectively using Logistic regression for risk factors associated with the development of post-surgical pulmonary complication. RESULTS: Post-surgical pulmonary complications was found in 12 out of the 82 patients studied, and it was the primarily death cause for one of them. Multivariate Logistic analysis identified advanced age[odds ratio (OR) = 1.28, 95% confidence interval (95% CI ) 1.05-1.62, P = 0.03], impaired pulmonary function [forced expiratory volume in one second (FEV1) OR = 1.20, 95% CI 1.08-1.39, P = 0.02] and longer operation duration (OR = 1.68, 95% CI 1.37-2.11, P = 0.003) as risk factors. CONCLUSION: Advanced age and impaired lung function may be significant risk factors for pulmonary complications after esophagectomy. It is helpful to evaluate the risk of such complications by referring to these indexes before the surgery, and design individualized treatment-plan for patients at high risk.