Mônica Santos1,2, Rodrigo Ribeiro-Rodrigues3, Carolina Talhari1,2, Luiz C L Ferreira1,4, Bernhard Zelger5, Sinesio Talhari1. 1. Department of Dermatology, Fundação de Medicina Tropical do Amazonas, Amazonas, Brazil. 2. Amazonas State University, Manaus, AM, Brazil. 3. Cellular and Molecular Immunology Lab., Núcleo de Doenças Infecciosas and Pathology Department, Universidade Federal do Espírito Santo, Vitória, Brazil. 4. Pathology Division, Fundação de Medicina Tropical do Amazonas, Amazonas, Brazil. 5. Department of Dermatology and Venerology, Innsbruck Medical University, Innsbruck, Austria.
Abstract
BACKGROUND: In the present study, Borrelia spirochetes were found in four (26.6%) out of 15 patients with Atrophoderma of Pasini and Pierini (IAPP) and lichen sclerosis et atrophicans (LSA) from the Brazilian Amazon Region. MATERIAL AND METHODS: Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 15 patients with both clinical and histopathology evidences compatible with Morphea, LSA, and IAPP. RESULTS: Spirochetes were detected by specific immunohistochemistry and focus floating microscopy for B. burgdorferi in samples from three patients. A limitation of our study was the fact that we were not able to isolate and culture these organisms. CONCLUSION: Our data confirm the presence of borreliosis cases in the Amazon.
BACKGROUND: In the present study, Borrelia spirochetes were found in four (26.6%) out of 15 patients with Atrophoderma of Pasini and Pierini (IAPP) and lichen sclerosis et atrophicans (LSA) from the Brazilian Amazon Region. MATERIAL AND METHODS: Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 15 patients with both clinical and histopathology evidences compatible with Morphea, LSA, and IAPP. RESULTS: Spirochetes were detected by specific immunohistochemistry and focus floating microscopy for B. burgdorferi in samples from three patients. A limitation of our study was the fact that we were not able to isolate and culture these organisms. CONCLUSION: Our data confirm the presence of borreliosis cases in the Amazon.
Authors: Elisa de Oliveira Barcaui; Antonio Carlos Pires Carvalho; Juan Piñeiro-Maceira; Carlos Baptista Barcaui Journal: An Bras Dermatol Date: 2019-10-17 Impact factor: 1.896
Authors: Felipe Ladeira de Oliveira; Luisa Kelmer Côrtes de Barros Silveira; Maria Lourdes Candela Rambaldi; Fabio Cuiabano Barbosa Journal: Case Rep Dermatol Med Date: 2012-11-21