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Literature DB >> 22002930

Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking.

Casey A Ydenberg¹, Benjamin A Smith, Dennis Breitsprecher, Jeff Gelles, Bruce L Goode.

Abstract

Membrane protrusion at the leading edge of migrating cells is driven by the polymerization of actin. Recent studies using advanced imaging techniques raised a lively controversy about the morphology of these filaments; however, common ground between the two sides now appears to have been found. Here we discuss how the controversy has led to a deeper consideration of the architecture of actin networks underlying cell migration, and has helped define new challenges that lie ahead.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Microfilament Proteins

Year: 2011 PMID： 22002930 PMCID： PMC3218376 DOI： 10.1002/cm.20543

Source DB: PubMed Journal: Cytoskeleton (Hoboken) ISSN： 1949-3592

62 in total

1. Functional synergy of actin filament cross-linking proteins.

Authors: Yiider Tseng; Benjamin W Schafer; Steven C Almo; Denis Wirtz
Journal: J Biol Chem Date: 2002-05-02 Impact factor: 5.157

2. VASP dynamics during lamellipodia protrusion.

Authors: K Rottner; B Behrendt; J V Small; J Wehland
Journal: Nat Cell Biol Date: 1999-09 Impact factor: 28.824

3. Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility.

Authors: James E Bear; Tatyana M Svitkina; Matthias Krause; Dorothy A Schafer; Joseph J Loureiro; Geraldine A Strasser; Ivan V Maly; Oleg Y Chaga; John A Cooper; Gary G Borisy; Frank B Gertler
Journal: Cell Date: 2002-05-17 Impact factor: 41.582

4. Visualizing branched actin filaments in lamellipodia by electron tomography.

Authors: Changsong Yang; Tatyana Svitkina
Journal: Nat Cell Biol Date: 2011-09-02 Impact factor: 28.824

5. Comparison of filamin A-induced cross-linking and Arp2/3 complex-mediated branching on the mechanics of actin filaments.

Authors: Fumihiko Nakamura; Eric Osborn; Paul A Janmey; Thomas P Stossel
Journal: J Biol Chem Date: 2002-01-10 Impact factor: 5.157

6. Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks.

Authors: L Blanchoin; T D Pollard; R D Mullins
Journal: Curr Biol Date: 2000-10-19 Impact factor: 10.834

Review 7. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells.

Authors: T D Pollard; L Blanchoin; R D Mullins
Journal: Annu Rev Biophys Biomol Struct Date: 2000

8. Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast.

Authors: Marie Evangelista; David Pruyne; David C Amberg; Charles Boone; Anthony Bretscher
Journal: Nat Cell Biol Date: 2002-03 Impact factor: 28.824

9. A biomimetic motility assay provides insight into the mechanism of actin-based motility.

Authors: Sebastian Wiesner; Emmanuele Helfer; Dominique Didry; Guylaine Ducouret; Françoise Lafuma; Marie-France Carlier; Dominique Pantaloni
Journal: J Cell Biol Date: 2003-01-27 Impact factor: 10.539

10. Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells.

Authors: L A Flanagan; J Chou; H Falet; R Neujahr; J H Hartwig; T P Stossel
Journal: J Cell Biol Date: 2001-11-12 Impact factor: 10.539

17 in total

1. Distributed actin turnover in the lamellipodium and FRAP kinetics.

Authors: Matthew B Smith; Tai Kiuchi; Naoki Watanabe; Dimitrios Vavylonis
Journal: Biophys J Date: 2013-01-08 Impact factor: 4.033

2. Visualization of uncorrelated, tandem symmetry mismatches in the internal genome packaging apparatus of bacteriophage T7.

Authors: Fei Guo; Zheng Liu; Frank Vago; Yue Ren; Weimin Wu; Elena T Wright; Philip Serwer; Wen Jiang
Journal: Proc Natl Acad Sci U S A Date: 2013-04-11 Impact factor: 11.205

Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking.

1. Functional synergy of actin filament cross-linking proteins.

2. VASP dynamics during lamellipodia protrusion.

3. Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility.

4. Visualizing branched actin filaments in lamellipodia by electron tomography.

5. Comparison of filamin A-induced cross-linking and Arp2/3 complex-mediated branching on the mechanics of actin filaments.

6. Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks.

Review 7. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells.

8. Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast.

9. A biomimetic motility assay provides insight into the mechanism of actin-based motility.

10. Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells.

1. Distributed actin turnover in the lamellipodium and FRAP kinetics.

2. Visualization of uncorrelated, tandem symmetry mismatches in the internal genome packaging apparatus of bacteriophage T7.

3. Novel roles for actin in mitochondrial fission.

Review 4. Quantitative computational models of molecular self-assembly in systems biology.

5. Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions.

6. Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin.

Review 7. Self-organization of protrusions and polarity during eukaryotic chemotaxis.

Review 8. Connecting the cytoskeleton to the endoplasmic reticulum and Golgi.

Review 9. Controlling the cortical actin motor.

Review 10. GMF as an Actin Network Remodeling Factor.