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8 in total

1. Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells.

Authors: Adelina Orellana; Vicente García-González; Rosa López; Sonia Pascual-Guiral; Estrella Lozoya; Julia Díaz; Daniel Casals; Antolín Barrena; Stephane Paris; Miriam Andrés; Victor Segarra; Dolors Vilella; Rajneesh Malhotra; Paul Eastwood; Anna Planagumà; Montserrat Miralpeix; Arsenio Nueda
Journal: PLoS One Date: 2018-01-10 Impact factor: 3.240

2. A New Quantitative Cell-Based Assay Reveals Unexpected Microtubule Stabilizing Activity of Certain Kinase Inhibitors, Clinically Approved or in the Process of Approval.

Authors: Sacnicte Ramirez-Rios; Sophie Michallet; Leticia Peris; Caroline Barette; Clotilde Rabat; Yangbo Feng; Marie-Odile Fauvarque; Annie Andrieux; Karin Sadoul; Laurence Lafanechère
Journal: Front Pharmacol Date: 2020-04-30 Impact factor: 5.810

3. Synthesis and Anticancer Activity of Mitotic-Specific 3,4-Dihydropyridine-2(1H)-thiones.

Authors: Magdalena Perużyńska; Aleksandra Borzyszkowska-Ledwig; Jacek G Sośnicki; Łukasz Struk; Tomasz J Idzik; Gabriela Maciejewska; Łukasz Skalski; Katarzyna Piotrowska; Paweł Łukasik; Marek Droździk; Mateusz Kurzawski
Journal: Int J Mol Sci Date: 2021-02-28 Impact factor: 5.923

Nocodazole is a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK.

1. Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells.

2. A New Quantitative Cell-Based Assay Reveals Unexpected Microtubule Stabilizing Activity of Certain Kinase Inhibitors, Clinically Approved or in the Process of Approval.

3. Synthesis and Anticancer Activity of Mitotic-Specific 3,4-Dihydropyridine-2(1H)-thiones.

Review 4. The microtubule cytoskeleton: An old validated target for novel therapeutic drugs.

5. Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer.

6. Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization.

Review 7. Microtubule Depolymerization by Kinase Inhibitors: Unexpected Findings of Dual Inhibitors.

8. Theoretical study of the geometric and electronic characterization of carbendazim-based drug (Nocodazole).