Literature DB >> 22002170

Inverse electron-demand Diels-Alder reactions for the selective and efficient labeling of RNA.

Juliane Schoch1, Sandeep Ameta, Andres Jäschke.   

Abstract

We report the first example of RNA labeling based on inverse electron-demand Diels-Alder reactions. Both chemically synthesized and enzymatically transcribed RNAs were successfully modified with biotin or a fluorescent label. This approach works efficiently under mild conditions in water and does not require transition metals.

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Year:  2011        PMID： 22002170     DOI： 10.1039/c1cc15476a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  14 in total

1.  mRNAs biotinylated within the 5' cap and protected against decapping: new tools to capture RNA-protein complexes.

Authors:  Sylwia Bednarek; Vanesa Madan; Pawel J Sikorski; Ralf Bartenschlager; Joanna Kowalska; Jacek Jemielity
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-11-05       Impact factor: 6.237

2.  μHall chip for sensitive detection of bacteria.

Authors:  David Issadore; Hyun Jung Chung; Jaehoon Chung; Ghyslain Budin; Ralph Weissleder; Hakho Lee
Journal:  Adv Healthc Mater       Date:  2013-03-12       Impact factor: 9.933

3.  Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides.

Authors:  Manisha B Walunj; Seergazhi G Srivatsan
Journal:  Bioconjug Chem       Date:  2020-10-22       Impact factor: 4.774

4.  Bioorthogonal chemistry-based RNA labeling technologies: evolution and current state.

Authors:  Jerrin Thomas George; Seergazhi G Srivatsan
Journal:  Chem Commun (Camb)       Date:  2020-10-07       Impact factor: 6.222

5.  Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing.

Authors:  Zexiang Chen; Gitali Devi; Amena Arif; Phillip D Zamore; Erik J Sontheimer; Jonathan K Watts
Journal:  ACS Chem Biol       Date:  2022-04-21       Impact factor: 4.634

6.  Nucleotidyl transferase assisted DNA labeling with different click chemistries.

Authors:  Marie-Luise Winz; Eva Christina Linder; Timon André; Juliane Becker; Andres Jäschke
Journal:  Nucleic Acids Res       Date:  2015-05-26       Impact factor: 16.971

Review 7.  Bio-orthogonal Fluorescent Labelling of Biopolymers through Inverse-Electron-Demand Diels-Alder Reactions.

Authors:  Eszter Kozma; Orsolya Demeter; Péter Kele
Journal:  Chembiochem       Date:  2017-02-01       Impact factor: 3.164

8.  Enzymatic modification of 5'-capped RNA with a 4-vinylbenzyl group provides a platform for photoclick and inverse electron-demand Diels-Alder reaction.

Authors:  Josephin Marie Holstein; Daniela Stummer; Andrea Rentmeister
Journal:  Chem Sci       Date:  2014-11-26       Impact factor: 9.825

9.  Facile and efficient Lewis acid catalyzed synthesis of an asymmetric tetrazine useful for bio-orthogonal click chemistry applications.

Authors:  Daniel L Alge; Dillon F Donohue; Kristi S Anseth
Journal:  Tetrahedron Lett       Date:  2013-10-09       Impact factor: 2.415

10.  Quantum Chemical Calculations and Experimental Validation of the Photoclick Reaction for Fluorescent Labeling of the 5' cap of Eukaryotic mRNAs.

Authors:  Daniela Stummer; Carmen Herrmann; Andrea Rentmeister
Journal:  ChemistryOpen       Date:  2015-02-04       Impact factor: 2.911
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