PURPOSE OF REVIEW: Laryngeal reinnervation for bilateral vocal fold paralysis (BVFP) patients is a promising technique to achieve good airway, although preserving a good quality of voice. On the other hand, the procedure is not simple. This review explores the recent literature on surgical technique and factors that may contribute to the success. RECENT FINDINGS: Research and literature in this area are limited due to variability and complexity of the nerve supply. The posterior cricoarytenoid (PCA) muscle also receives nerve supply from the interarytenoid branch. Transection of this nerve at the point between interarytenoid and PCA branch may prevent aberrant reinnervation of adductor nerve axons to the PCA muscle. A varying degree of regeneration of injured recurrent laryngeal nerves (RLN) in humans of more than 6 months confirms subclinical reinnervation, which may prevent denervation-induced atrophy. SUMMARY: Several promising surgical techniques have been developed for bilateral selective reinnervation for BVFP patients. This involves reinnervation of the abductor and adductor laryngeal muscles. The surgical technique aims at reinnervating the PCA muscle to trigger abduction during the respiratory cycle and preservation of good voice by strengthening the adductor muscles as well as prevention of laryngeal synkinesis.
PURPOSE OF REVIEW: Laryngeal reinnervation for bilateral vocal fold paralysis (BVFP) patients is a promising technique to achieve good airway, although preserving a good quality of voice. On the other hand, the procedure is not simple. This review explores the recent literature on surgical technique and factors that may contribute to the success. RECENT FINDINGS: Research and literature in this area are limited due to variability and complexity of the nerve supply. The posterior cricoarytenoid (PCA) muscle also receives nerve supply from the interarytenoid branch. Transection of this nerve at the point between interarytenoid and PCA branch may prevent aberrant reinnervation of adductor nerve axons to the PCA muscle. A varying degree of regeneration of injured recurrent laryngeal nerves (RLN) in humans of more than 6 months confirms subclinical reinnervation, which may prevent denervation-induced atrophy. SUMMARY: Several promising surgical techniques have been developed for bilateral selective reinnervation for BVFP patients. This involves reinnervation of the abductor and adductor laryngeal muscles. The surgical technique aims at reinnervating the PCA muscle to trigger abduction during the respiratory cycle and preservation of good voice by strengthening the adductor muscles as well as prevention of laryngeal synkinesis.
Authors: Yarah M Haidar; Ronald Sahyouni; Omid Moshtaghi; Beverly Y Wang; Hamid R Djalilian; John C Middlebrooks; Sunil P Verma; Harrison W Lin Journal: Laryngoscope Date: 2017-10-31 Impact factor: 3.325
Authors: Vera Matievics; Adam Bach; Balazs Sztano; Zsofia Bere; Zoltan Tobias; Paul F Castellanos; Andreas H Mueller; Laszló Rovo Journal: Eur Arch Otorhinolaryngol Date: 2017-08-08 Impact factor: 2.503
Authors: Janet W Lee; Nicolas Bon-Mardion; Marshall E Smith; Jean-Paul Marie Journal: JAMA Otolaryngol Head Neck Surg Date: 2020-05-01 Impact factor: 6.223
Authors: Jean Michel Prades; M Gavid; M D Dubois; J M Dumollard; A T Timoshenko; M Peoc'h Journal: Surg Radiol Anat Date: 2014-08-28 Impact factor: 1.246
Authors: Yike Li; Elizabeth C Pearce; Rajshri Mainthia; Sanjay M Athavale; Jennifer Dang; Daniel H Ashmead; C Gaelyn Garrett; Bernard Rousseau; Cheryl R Billante; David L Zealear Journal: ORL J Otorhinolaryngol Relat Spec Date: 2013-05-30 Impact factor: 1.538