Literature DB >> 22001087

Discovery of small molecules that enhance astrocyte differentiation in rat fetal neural stem cells.

Dong Jo Chang1, Mi Young Jeong, Jiho Song, Chang Yun Jin, Young-Ger Suh, Hyun-Jung Kim, Kyung Hoon Min.   

Abstract

1,3,4-Oxadiazole derivatives were found to enhance astrocyte differentiation in rat fetal neural stem cells (NSCs). Differentiation activity was assessed by immunocytochemistry and analysis of mRNA expression of astrocyte markers, GFAP and S100. Compounds 7 and 8 showed approximately a two-fold increase in astrocyte differentiation without engagement of neuronal differentiation and detectable cytotoxicity. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22001087     DOI： 10.1016/j.bmcl.2011.09.099

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  Stem cells in drug screening for neurodegenerative disease.

Authors:  Hyun-Jung Kim; Chang Yun Jin
Journal:  Korean J Physiol Pharmacol       Date:  2012-02-28       Impact factor: 2.016

2.  Hyperbaric oxygen therapy improves local microenvironment after spinal cord injury.

Authors:  Yang Wang; Shuquan Zhang; Min Luo; Yajun Li
Journal:  Neural Regen Res       Date:  2014-12-15       Impact factor: 5.135

3.  Quantitative and qualitative analysis of the novel antitumor 1,3,4-oxadiazole derivative (GLB) and its metabolites using HPLC-UV and UPLC-QTOF-MS.

Authors:  Pu Li; Xin Wang; Jian Li; Zhi-Yun Meng; Shu-Chun Li; Zhong-Jun Li; Ying-Yuan Lu; Hong Ren; Ya-Qing Lou; Chuang Lu; Gui-Fang Dou; Guo-Liang Zhang
Journal:  Sci Rep       Date:  2015-07-07       Impact factor: 4.379

4.  Kuwanon V inhibits proliferation, promotes cell survival and increases neurogenesis of neural stem cells.

Authors:  Sun-Young Kong; Min-Hye Park; Mina Lee; Jae-Ouk Kim; Ha-Rim Lee; Byung Woo Han; Clive N Svendsen; Sang Hyun Sung; Hyun-Jung Kim
Journal:  PLoS One       Date:  2015-02-23       Impact factor: 3.240

5.  Umbilical cord-derived mesenchymal stem cell transplantation combined with hyperbaric oxygen treatment for repair of traumatic brain injury.

Authors:  Hai-Xiao Zhou; Zhi-Gang Liu; Xiao-Jiao Liu; Qian-Xue Chen
Journal:  Neural Regen Res       Date:  2016-01       Impact factor: 5.135

6.  Indole Alkaloids Inhibiting Neural Stem Cell from Uncaria rhynchophylla.

Authors:  Xin Wei; Li-Ping Jiang; Ying Guo; Afsar Khan; Ya-Ping Liu; Hao-Fei Yu; Bei Wang; Cai-Feng Ding; Pei-Feng Zhu; Ying-Ying Chen; Yun-Li Zhao; Yong-Bing Chen; Yi-Fen Wang; Xiao-Dong Luo
Journal:  Nat Prod Bioprospect       Date:  2017-09-26

7.  Functional Group-Dependent Induction of Astrocytogenesis and Neurogenesis by Flavone Derivatives.

Authors:  Ha-Rim Lee; Jin Mi Kang; Young Min Kim; Sagang Kim; Jihyae Ann; Jeewoo Lee; Hyun-Jung Kim
Journal:  Biomolecules       Date:  2019-12-02

8.  Cell density-dependent differential proliferation of neural stem cells on omnidirectional nanopore-arrayed surface.

Authors:  Kyoung Je Cha; Sun-Young Kong; Ji Soo Lee; Hyung Woo Kim; Jae-Yeon Shin; Moonwoo La; Byung Woo Han; Dong Sung Kim; Hyun-Jung Kim
Journal:  Sci Rep       Date:  2017-10-12       Impact factor: 4.379

9.  Proteasome Inhibitor MG132 is Toxic and Inhibits the Proliferation of Rat Neural Stem Cells but Increases BDNF Expression to Protect Neurons.

Authors:  Young Min Kim; Hyun-Jung Kim
Journal:  Biomolecules       Date:  2020-11-02
  9 in total

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