| Literature DB >> 22001031 |
Seizo Sato1, Fumie Iwata, Shoichi Yamada, Hiroyuki Kawahara, Masashi Katayama.
Abstract
New anthramycin-type analogues, designated usabamycin A-C (1, 2 and 3), have been isolated from cultures of Streptomyces sp. NPS853, a bacterium found in marine sediments. The structures of the new compounds were established on the basis of extensive spectroscopic analyses including 1D- and 2D-NMR ((1)H-(1)H COSY, HSQC, and HMBC) experiments. The usabamycins show weak inhibition of HeLa cell growth and selective inhibition of serotonin (5-hydroxytrypamine) 5-HT(2B) uptake. Copyright ÂEntities:
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Year: 2011 PMID： 22001031 DOI： 10.1016/j.bmcl.2011.09.086
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823