PURPOSE: We sought to distinguish roles of demographic variables and bowel segments as predictors of delayed versus early stage colorectal cancer in California. METHODS: Demographic and anatomic variables for 66,806 colorectal cancers were extracted from the California Cancer Registry for 2004-2008 and analyzed using logistic regression as delayed versus early stage. RESULTS: Odds ratios (OR) for binary stage categories comparing age <40 (OR=2.58; 95% CI=2.26-2.94), 40-49 (1.71; 95%=1.60-1.83) and 75+ (1.05; 1.02-1.09) relative to 50-74 years were computed. Compared with non-Hispanic whites, ORs for stage categories were: 1.05; 0.99-1.13 (non-Hispanic blacks), 1.08; 1.02-1.13 (Hispanics), and 1.05; 1.00-1.10 (Asian/others). Females had higher odds of delayed diagnosis (1.09; 1.06-1.13) than males. Descending ORs were measured for successively lower to highest socioeconomic status (SES) quintiles (OR 4:5=1.08; 1.03-1.14, OR 3:5=1.13; 1.08-1.19, OR 2:5=1.18; 1.12- 1.24, and OR 1:5=1.21; 1.14-1.28). CONCLUSIONS: Younger and older than age 50-74; females; Hispanic ethnicity; bowel segment contrasts (right/left, proximal/distal, cecum plus appendix/distal), and lower SES were independent predictors of delayed diagnosis. Low SES was the most robust predictor of delayed diagnosis, independent of other covariates. Approximately 77% of delayed diagnoses were in non-Hispanic whites and Asian/others. These findings illustrate the value of a community SES index for targeting egalitarian colorectal cancer screening. Copyright Â
PURPOSE: We sought to distinguish roles of demographic variables and bowel segments as predictors of delayed versus early stage colorectal cancer in California. METHODS: Demographic and anatomic variables for 66,806 colorectal cancers were extracted from the California Cancer Registry for 2004-2008 and analyzed using logistic regression as delayed versus early stage. RESULTS: Odds ratios (OR) for binary stage categories comparing age <40 (OR=2.58; 95% CI=2.26-2.94), 40-49 (1.71; 95%=1.60-1.83) and 75+ (1.05; 1.02-1.09) relative to 50-74 years were computed. Compared with non-Hispanic whites, ORs for stage categories were: 1.05; 0.99-1.13 (non-Hispanic blacks), 1.08; 1.02-1.13 (Hispanics), and 1.05; 1.00-1.10 (Asian/others). Females had higher odds of delayed diagnosis (1.09; 1.06-1.13) than males. Descending ORs were measured for successively lower to highest socioeconomic status (SES) quintiles (OR 4:5=1.08; 1.03-1.14, OR 3:5=1.13; 1.08-1.19, OR 2:5=1.18; 1.12- 1.24, and OR 1:5=1.21; 1.14-1.28). CONCLUSIONS: Younger and older than age 50-74; females; Hispanic ethnicity; bowel segment contrasts (right/left, proximal/distal, cecum plus appendix/distal), and lower SES were independent predictors of delayed diagnosis. Low SES was the most robust predictor of delayed diagnosis, independent of other covariates. Approximately 77% of delayed diagnoses were in non-Hispanic whites and Asian/others. These findings illustrate the value of a community SES index for targeting egalitarian colorectal cancer screening. Copyright Â
Authors: Samir Gupta; Daniel A Sussman; Chyke A Doubeni; Daniel S Anderson; Lukejohn Day; Amar R Deshpande; B Joseph Elmunzer; Adeyinka O Laiyemo; Jeanette Mendez; Ma Somsouk; James Allison; Taft Bhuket; Zhuo Geng; Beverly B Green; Steven H Itzkowitz; Maria Elena Martinez Journal: J Natl Cancer Inst Date: 2014-03-28 Impact factor: 13.506
Authors: Kevin M Gorey; Isaac N Luginaah; Eric J Holowaty; Guangyong Zou; Caroline Hamm; Emma Bartfay; Sindu M Kanjeekal; Madhan K Balagurusamy; Sundus Haji-Jama; Frances C Wright Journal: BMC Public Health Date: 2012-10-24 Impact factor: 3.295
Authors: Cristina Sarasqueta; Mª Victoria Zunzunegui; José María Enríquez Navascues; Arrate Querejeta; Carlos Placer; Amaia Perales; Nerea Gonzalez; Urko Aguirre; Marisa Baré; Antonio Escobar; José María Quintana Journal: BMC Cancer Date: 2020-08-14 Impact factor: 4.430