| Literature DB >> 219988 |
E Nieschlag, H Hoogen, M Bölk, H Schuster, E J Wickings.
Abstract
The newly available orally effective testosterone undecanoate (TU) was investigated as a possible means for male fertility control. One of 7 normal volunteers exposed to 80 mg TU three times a day for 10-12 weeks became azoospermic, the remaining showed slightly suppressed or unaffected sperm counts. The insufficient suppression of spermatogenesis in 6 out of 7 subjects may be due to the fact that testosterone levels are only sufficiently high to suppress gonadotropins for some hours after ingestion of the drug.Entities:
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Year: 1978 PMID： 219988 DOI： 10.1016/0010-7824(78)90045-8
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375