Neurocutaneous melanosis in association with proliferative skin nodules.

We report the case of a 15-year-old boy with giant congenital melanocytic nevi on his back, buttocks, and rear of the two proximal thirds of his thighs, and neurocutaneous melanosis, diagnosed when he was 3 years old. Three melanocytic nodules were present in the giant nevi that were suspected to have malignant degeneration. A biopsy of these nodules was carried out, and histological study revealed benign proliferative melanocytic nodules within the giant congenital melanocytic nevi.