Literature DB >> 2199565

[Parkinson disease and pregnancy. Apropos of a case].

F Jacquemard1, J C Palaric, H Allain, J R Giraud.   

Abstract

Parkinson's disease is a neurological condition associated with neuronal degeneration in the corpora nigra with a drop in the level of dopamine in the striatum. It is rarely encountered in women of reproductive age. Treatment is by giving levodopa. We report a case of pregnancy in a woman of 34 years of age who was suffering from severe Parkinson's disease treated with levodopa. We have assessed this case in the light of viewing the literature which confirms that there is no effect on the pregnancy or on the fetus although the symptoms of Parkinson's disease are made worse. Levodopa seems to be quite innocuous as far as the fetus is concerned. There is no teratogenicity although in animal experiments high doses teratogenic effects have been noted.

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Year:  1990        PMID: 2199565

Source DB:  PubMed          Journal:  J Gynecol Obstet Biol Reprod (Paris)        ISSN: 0150-9918


  5 in total

1.  Pregnancy management and outcome in patients with four different tetrahydrobiopterin disorders.

Authors:  O Kuseyri; A Weissbach; N Bruggemann; C Klein; M Giżewska; D Karall; S Scholl-Bürgi; H Romanowska; E Krzywińska-Zdeb; A A Monavari; I Knerr; Z Yapıcı; V Leuzzi; T Opladen
Journal:  J Inherit Metab Dis       Date:  2018-03-28       Impact factor: 4.982

2.  Successful birth of an IVF baby in a patient with Parkinson's disease.

Authors:  Baxi Asha; Neema Hansali; Pauranik Apoorva
Journal:  J Hum Reprod Sci       Date:  2010-01

3.  Maternal tetrahydrobiopterin deficiency: the course of two pregnancies and follow-up of two children in a mother with 6-pyruvoyl-tetrahydropterin synthase deficiency.

Authors:  M Giżewska; G Hnatyszyn; L Sagan; L Cyryłowski; C Zekanowski; M Modrzejewska; B Nestorowicz; J Kubalska; M Walczak
Journal:  J Inherit Metab Dis       Date:  2009-03-30       Impact factor: 4.982

4.  Two cases of pregnancy in Parkinson's disease.

Authors:  Dronacharya Lamichhane; N S Narayanan; Pedro Gonzalez-Alegre
Journal:  Parkinsonism Relat Disord       Date:  2013-10-20       Impact factor: 4.891

5.  Management of Parkinson's Disease During Pregnancy: Literature Review and Multidisciplinary Input.

Authors:  Caitlin Young; Rhiannon Phillips; Louise Ebenezer; Rodi Zutt; Kathryn J Peall
Journal:  Mov Disord Clin Pract       Date:  2020-04-09
  5 in total

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