Literature DB >> 21992173

Effective use of negative pressure wound therapy provides quick wound-bed preparation and complete graft take in the management of chronic venous ulcers.

Onur Egemen1, Ozay Ozkaya, Muhammed Besir Ozturk, Tolga Aksan, Çağdaş Orman, Mithat Akan.   

Abstract

Venous ulcers are characterised by longstanding and recurrent loss of skin integrity. Once occurred, healing is slow and recurrence is high because of inappropriate conditions of the wound bed. This study involves 20 patients with chronic venous ulcers at least 6 weeks of duration treated with negative pressure wound therapy (NPWT). Patients underwent a radical debridement of all devitalised tissues in the first operation. After adequate haemostasis, silver-impregnated polyurethane foam was applied. Once the wounds were determined to be clean and adequate granulation tissue formation was achieved, split-thickness skin grafts were applied. Black polyurethane foam was applied over them. All wounds completely healed without the need for further debridement or regrafting. The mean number of silver-impregnated foam dressing changes prior to grafting was 2·9 (one to eight changes). The mean number of NPWT foam changes was 2·6 after skin grafting (two to five changes). Two patients who did not use conservative treatments for chronic venous insufficiency (CVI) after discharge from the hospital had recurrence of venous ulcers in the follow-up period. Application of NPWT provides quick wound-bed preparation and complete graft take in venous ulcer treatment.
© 2011 The Authors. © 2011 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

Entities:  

Mesh:

Year:  2011        PMID: 21992173      PMCID: PMC7950862          DOI: 10.1111/j.1742-481X.2011.00876.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  48 in total

Review 1.  Pathophysiology of venous ulcers: surgical implications, review, and update.

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Review 3.  Medical and surgical therapy for advanced chronic venous insufficiency.

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Authors:  Nima P Patel; Nicos Labropoulos; Peter J Pappas
Journal:  Plast Reconstr Surg       Date:  2006-06       Impact factor: 4.730

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Authors:  Joanne E Paddle-Ledinek; Zeyad Nasa; Heather J Cleland
Journal:  Plast Reconstr Surg       Date:  2006-06       Impact factor: 4.730

Review 6.  Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers.

Authors:  David L Steed
Journal:  Plast Reconstr Surg       Date:  2006-06       Impact factor: 4.730

7.  Daflon 500 mg and venous leg ulcer: new results from a meta-analysis.

Authors:  Philip Coleridge Smith
Journal:  Angiology       Date:  2005 Sep-Oct       Impact factor: 3.619

8.  The difficult venous ulcer: case series of 177 ulcers referred for vascular surgical opinion following failure of conservative management.

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Journal:  Angiology       Date:  2009-04-26       Impact factor: 3.619

9.  Influence of a specialised leg ulcer service and venous surgery on the outcome of venous leg ulcers.

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Journal:  Eur J Vasc Endovasc Surg       Date:  1998-09       Impact factor: 7.069

Review 10.  Systematic review of outcomes after surgical management of venous disease incorporating subfascial endoscopic perforator surgery.

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Journal:  J Vasc Surg       Date:  2004-03       Impact factor: 4.268

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  9 in total

1.  Negative-pressure wound dressings to secure split-thickness skin grafts in the perineum.

Authors:  Kyeong-Tae Lee; Jai-Kyong Pyon; So-Young Lim; Goo-Hyun Mun; Kap Sung Oh; Sa-Ik Bang
Journal:  Int Wound J       Date:  2012-09-07       Impact factor: 3.315

2.  Topical negative pressure coupled with split-thickness skin grafting for the treatment of hidradenitis suppurativa: a case report.

Authors:  Tang Jianbing; Cheng Biao; Li Qin; Wu Yanhong
Journal:  Int Wound J       Date:  2013-07-09       Impact factor: 3.315

3.  Management of chronic osteomyelitis of the tibia with life-threatening complications under negative pressure wound therapy and isolation of Helcococcus kunzii.

Authors:  Katrin M Stanger; Frauke Albert; Ulrich Kneser; Christian Bogdan; Raymund E Horch
Journal:  Int Wound J       Date:  2013-07-16       Impact factor: 3.315

Review 4.  Insulin and hypertonic glucose in the management of aseptic fat liquefaction of post-surgical incision: a meta-analysis and systematic review.

Authors:  Zhongjie Shi; Lin Ma; Hao Wang; Yuebo Yang; Xiaomao Li; Ann Schreiber; Wenjing Sun; Zhanliang Hu; Yuhua Xue; Jiafeng Teng; Xuan Zhao; Wenli Lu
Journal:  Int Wound J       Date:  2012-02-10       Impact factor: 3.315

5.  Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?

Authors:  Christopher Ward; David Ciraulo; Michael Coulter; Steven Desjardins; Lucy Liaw; Sarah Peterson
Journal:  J Trauma Acute Care Surg       Date:  2012-08       Impact factor: 3.313

Review 6.  Pain and trauma in negative pressure wound therapy: a review.

Authors:  Dominic Upton; Abbye Andrews
Journal:  Int Wound J       Date:  2013-03-12       Impact factor: 3.315

7.  Retention of polyurethane foam fragments during VAC therapy: a complication to be considered.

Authors:  Luca A Dessy; Francesco Serratore; Federico Corrias; Paola Parisi; Marco Mazzocchi; Bruno Carlesimo
Journal:  Int Wound J       Date:  2013-04-17       Impact factor: 3.315

8.  Limb salvage procedure in immunocompromised patients with therapy-resistant leg ulcers-The value of ultra-radical debridement and instillation negative-pressure wound therapy.

Authors:  Alexander Geierlehner; Raymund E Horch; Wibke Müller-Seubert; Andreas Arkudas; Ingo Ludolph
Journal:  Int Wound J       Date:  2020-06-22       Impact factor: 3.315

Review 9.  Heel Pressure Injuries: Consensus-Based Recommendations for Assessment and Management.

Authors:  Massimo Rivolo; Sara Dionisi; Diletta Olivari; Guido Ciprandi; Serena Crucianelli; Silvia Marcadelli; Rosa Rita Zortea; Fabio Bellini; Matteo Martinato; Armando Gabrielli; Giovanni Pomponio
Journal:  Adv Wound Care (New Rochelle)       Date:  2019-10-21       Impact factor: 4.730

  9 in total

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