Literature DB >> 21991941

Postmortem examinations on deceased neonates: a rarely utilized procedure in an African referral center.

Ezekiel E Ugiagbe1, Osarumwense D Osifo.   

Abstract

Postmortem examination remains the gold standard for the correct diagnosis of many diseases and for unraveling unexplained causes of death. This paper reports on the poor utilization of autopsy services and encourages parents/caregivers and practitioners to perform postmortem examinations on deceased neonates in sub-Saharan Africa. In a retrospective study, the records of 1093 neonates (653 males and 440 females, ratio 1.5∶1) who died at the University of Benin Teaching Hospital and who were brought to the mortuary between 2006 and 2010 were reviewed to determine the utilization of and factors influencing postmortem examination. Sixty-two percent of the neonates died within the 1st week of life, and only 9 (0.8%) underwent a postmortem examination. Findings in the 9 postmortem studies performed on 7 males and 2 females provided additional information on the causes of death. The religious beliefs that neonates should not be subjected to postmortem study and beliefs that dead neonates are taboo and a punishment by the gods for past wrongdoings influenced 511 (46.8%) parents/caregivers to refuse postmortem analysis. The practitioners did not request postmortem study in 281 (25.7%) of the cases. The utilization of postmortem examination was marginal in this setting. We advocate the need for public enlightenment campaigns to modify the attitudes of parents/caregivers toward the postmortem study of deceased neonates. Policies should be formulated to mandate postmortem examinations of deceased neonates to enhance insight into neonatal disease, unravel unexplained causes of death, and improve the standard of neonatal care in this subregion.

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Year:  2011        PMID: 21991941     DOI: 10.2350/10-12-0952-OA.1

Source DB:  PubMed          Journal:  Pediatr Dev Pathol        ISSN: 1093-5266


  13 in total

1.  Rumor surveillance in support of minimally invasive tissue sampling for diagnosing the cause of child death in low-income countries: A qualitative study.

Authors:  Md Saiful Islam; Abdullah Al-Masud; Maria Maixenchs; Saquina Cossa; Rui Guilaze; Kounandji Diarra; Issa Fofana; Faruqe Hussain; John Blevins; Ahoua Kone; Shams El Arifeen; Inácio Mandomando; Quique Bassat; Elizabeth O'Mara Sage; Emily S Gurley; Khátia Munguambe
Journal:  PLoS One       Date:  2021-01-28       Impact factor: 3.240

2.  Pathological Methods Applied to the Investigation of Causes of Death in Developing Countries: Minimally Invasive Autopsy Approach.

Authors:  Paola Castillo; Esperança Ussene; Mamudo R Ismail; Dercio Jordao; Lucilia Lovane; Carla Carrilho; Cesaltina Lorenzoni; Marcus V Lacerda; Antonio Palhares; Leonardo Rodríguez-Carunchio; Miguel J Martínez; Jordi Vila; Quique Bassat; Clara Menéndez; Jaume Ordi
Journal:  PLoS One       Date:  2015-06-30       Impact factor: 3.240

Review 3.  Congenital anomalies in low- and middle-income countries: the unborn child of global surgery.

Authors:  Nicole A Sitkin; Doruk Ozgediz; Peter Donkor; Diana L Farmer
Journal:  World J Surg       Date:  2015-01       Impact factor: 3.352

4.  Willingness to Know the Cause of Death and Hypothetical Acceptability of the Minimally Invasive Autopsy in Six Diverse African and Asian Settings: A Mixed Methods Socio-Behavioural Study.

Authors:  Maria Maixenchs; Rui Anselmo; Emily Zielinski-Gutiérrez; Frank O Odhiambo; Clarah Akello; Maureen Ondire; S Shujaat H Zaidi; Sajid Bashir Soofi; Zulfiqar A Bhutta; Kounandji Diarra; Mahamane Djitèye; Roukiatou Dembélé; Samba Sow; Pamela Cathérine Angoissa Minsoko; Selidji Todagbe Agnandji; Bertrand Lell; Mamudo R Ismail; Carla Carrilho; Jaume Ordi; Clara Menéndez; Quique Bassat; Khátia Munguambe
Journal:  PLoS Med       Date:  2016-11-22       Impact factor: 11.069

5.  Validity of a Minimally Invasive Autopsy for Cause of Death Determination in Adults in Mozambique: An Observational Study.

Authors:  Paola Castillo; Miguel J Martínez; Esperança Ussene; Dercio Jordao; Lucilia Lovane; Mamudo R Ismail; Carla Carrilho; Cesaltina Lorenzoni; Fabiola Fernandes; Rosa Bene; Antonio Palhares; Luiz Ferreira; Marcus Lacerda; Inacio Mandomando; Jordi Vila; Juan Carlos Hurtado; Khátia Munguambe; Maria Maixenchs; Ariadna Sanz; Llorenç Quintó; Eusebio Macete; Pedro Alonso; Quique Bassat; Clara Menéndez; Jaume Ordi
Journal:  PLoS Med       Date:  2016-11-22       Impact factor: 11.069

Review 6.  Searching cause of death through different autopsy methods: A new initiative.

Authors:  Abhishek Das; Ranadip Chowdhury
Journal:  J Family Med Prim Care       Date:  2017 Apr-Jun

7.  Mortality Surveillance Methods to Identify and Characterize Deaths in Child Health and Mortality Prevention Surveillance Network Sites.

Authors:  Navit T Salzberg; Kasthuri Sivalogan; Quique Bassat; Allan W Taylor; Sunday Adedini; Shams El Arifeen; Nega Assefa; Dianna M Blau; Richard Chawana; Carrie Jo Cain; Kevin P Cain; J Patrick Caneer; Mischka Garel; Emily S Gurley; Reinhard Kaiser; Karen L Kotloff; Inacio Mandomando; Timothy Morris; Peter Nyamthimba Onyango; Hossain M S Sazzad; J Anthony G Scott; Anna C Seale; Antonio Sitoe; Samba O Sow; Milagritos D Tapia; Ellen A Whitney; Mary Claire Worrell; Emily Zielinski-Gutierrez; Shabir A Madhi; Pratima L Raghunathan; Jeffrey P Koplan; Robert F Breiman
Journal:  Clin Infect Dis       Date:  2019-10-09       Impact factor: 9.079

Review 8.  Sudden infant death syndrome: an unrecognized killer in developing countries.

Authors:  Ikenna Kingsley Ndu
Journal:  Pediatric Health Med Ther       Date:  2016-02-03

9.  Perceptions of parents and healthcare professionals regarding minimal invasive tissue sampling to identify the cause of death in stillbirths and neonates: a qualitative study protocol.

Authors:  Anam Feroz; Mohsina Noor Ibrahim; Shiyam Sunder Tikmani; Sayyeda Reza; Zahid Abbasi; Jamal Raza; Haleema Yasmin; Khadija Bano; Afia Zafar; Elizabeth M McClure; Robert L Goldenberg; Sarah Saleem
Journal:  Reprod Health       Date:  2018-10-22       Impact factor: 3.223

10.  Minimally Invasive Tissue Sampling in Preterm Deaths: A Validation Study.

Authors:  Rahell Hailu; Tigist Desta; Yonas Bekuretsion; Messele Bezabih; Addisu Alemu; Tiruzer Bekele; Bewketu Abebe; Mesfin Asefa; Zemene Tigabu; Yonas Girma; Beza Eshetu; Mahlet Abayneh; Amha Mekasha; Assaye Kassie Nigussie; Elizabeth M McClure; Robert L Goldenberg; Lulu M Muhe
Journal:  Glob Pediatr Health       Date:  2020-08-28
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