Literature DB >> 21991755

Ten years experience of directly observed treatment short-course (dots) therapy for tuberculosis in Addis Ababa, Ethiopia.

Desalegn Woldeyohannes1, Nigatu Kebede, Woldaregay Erku, Zerihun Tadesse.   

Abstract

BACKGROUND: Tuberculosis (TB) is still the leading cause of death worldwide accounting for 2.5% of the global burden of disease and 25% of all avoidable deaths in developing countries.
OBJECTIVE: The aim of the study was to evaluate the impact of the Directly Observed Treatment-Short course (DOTS) programme in Addis Ababa, Ethiopia from 1998-2007.
METHODS: Institutional-based retrospective study was employed Reports using world health organization (WHO) format for TB case finding and treatment outcome from all Sub-cities of the city to the Federal Ministry of Health were collected
RESULTS: Between the years (1998-2007), 133,340 patients with all form of TB were registered. Of these, 40,929 (31%) were AFB + ve Pulmonary TB (PTB+ve), 48,491 (36%) were AFB-ve Pulmonary TB (PTB-ve), and 43,920 (33%) were Extra Pulmonary TB (EPTB) cases. The trend of case detection rate (CDR) for new smear positive pulmonary TB cases has increased from 73% in 1998 to its peak 113% in 2000 and then it decreased to 68% in 2007. The treatment success rate (TSR) has value with an average and standard deviation of 80% and 3.2, respectively from 1999 to 2007.
CONCLUSION: It is possible to achieve the recommended WHO target (70% CDR & 85% TSR) as can be seen how closely these targets were approached (68% & 81%, respectively) in the city in 2007; However, this requires seeking alternative case finding mechanisms.

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Year:  2011        PMID: 21991755

Source DB:  PubMed          Journal:  Ethiop Med J        ISSN: 0014-1755


  8 in total

1.  Directly Observed Treatment Short-course (DOTS) for tuberculosis control program in Gambella Regional State, Ethiopia: ten years experience.

Authors:  Solomon Sisay; Belete Mengistu; Woldaregay Erku; Desalegn Woldeyohannes
Journal:  BMC Res Notes       Date:  2014-01-20

2.  Trends of tuberculosis case notification and treatment outcomes in the Sidama Zone, southern Ethiopia: ten-year retrospective trend analysis in urban-rural settings.

Authors:  Mesay Hailu Dangisso; Daniel Gemechu Datiko; Bernt Lindtjørn
Journal:  PLoS One       Date:  2014-12-02       Impact factor: 3.240

3.  Treatment Outcome of Tuberculosis Patients under Directly Observed Treatment Short Course and Factors Affecting Outcome in Southern Ethiopia: A Five-Year Retrospective Study.

Authors:  Gebremedhin Gebrezgabiher; Gebremedhin Romha; Eyasu Ejeta; Getahun Asebe; Endalew Zemene; Gobena Ameni
Journal:  PLoS One       Date:  2016-02-26       Impact factor: 3.240

4.  Trends of unsuccessful treatment outcomes and associated factors among tuberculosis patients in public hospitals of Bale Zone, Southeast Ethiopia: A 5-year retrospective study.

Authors:  Demisu Zenbaba; Mitiku Bonsa; Biniyam Sahiledengle
Journal:  Heliyon       Date:  2021-09-11

5.  Directly observed treatment short-course (DOTS) for treatment of new tuberculosis cases in Somali Regional State, Eastern Ethiopia: ten years retrospective study.

Authors:  Desalegn Woldeyohannes; Solomon Sisay; Belete Mengistu; Hiwot Kassa
Journal:  BMC Res Notes       Date:  2015-08-19

6.  Treatment outcomes and their trend among tuberculosis patients treated at peripheral health settings of Northern Ethiopia between 2009 and 2014: a registry-based retrospective analysis.

Authors:  Mahmud Abdulkader; Ischa van Aken; Selam Niguse; Haftamu Hailekiros; Mark Spigt
Journal:  BMC Res Notes       Date:  2019-12-02

7.  Six Years Trend Analysis of Tuberculosis in Northwestern Tigrai, Ethiopia; 2019: A Retrospective Study.

Authors:  Hadush Negash; Haftom Legese; Gebre Adhanom; Fitsum Mardu; Kebede Tesfay; Senait Gebreslasie Gebremeskel; Brhane Berhe
Journal:  Infect Drug Resist       Date:  2020-02-24       Impact factor: 4.003

8.  Treatment outcome of tuberculosis patients under directly observed treatment in Addis Ababa, Ethiopia.

Authors:  Belete Getahun; Gobena Ameni; Girmay Medhin; Sibhatu Biadgilign
Journal:  Braz J Infect Dis       Date:  2013-07-02       Impact factor: 3.257

  8 in total

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