Clinical and bacteriological profile of urinary tract infection in children at Nepal Medical College Teaching Hospital.

The aim of this study was to study the clinical and bacteriological profile of urinary tract infection (UTI) in children. This was a prospective study of 40 culture positive cases of UTI in children who attended pediatric outpatient department of Nepal Medical College Teaching Hospital. UTI was more common in female (65.0%) than in male (35.0%). Half were in the age group 1- 5 years. Fever was the most common presentation (65.0%) followed by abdominal pain (42.5%), decreased appetite (37.5%) and dysuria (37.5%). Escherichia coli was the most common (67.5%) bacterial isolate followed by Klebsiella sps (20.0%) and Proteus sps (10.0%). E. coli was 100 % sensitive to nitrofurantoin. E. coli was also highly sensitive to ofloxacin, cefotaxim and amikacin (94.0%). Klebsiella was 100 % sensitive to ciprofloxacin and amikacin. Greater degree of resistance was seen to ampicillin, cotrimoxazole and nalidixic acid.