Literature DB >> 21991166

Disorders of the immune system in severely burned patients.

A D Fayazov1, S I Shukurov, B I Shukurov, B C Sultanov, A N Namazov, D A Ruzimuratov.   

Abstract

This paper analyses the results of immunological examinations of 124 patients with thermal injury. We examined indices of peripheral blood such us the size of the population of circulating T-lymphocytes (CD3), T-helpers (CD4), T-suppressors (CD8 and CD25), natural cell killers (CD16), transmembrane protein of apoptotic activity (CD16), B-lymphocytes, phagocyte activity of lymphocytes, and the level of serum antibody of the basic classes (Ig G, A, M). It was discovered that the burn disease was accompanied by deeply marked secondary immune deficiency primarily caused by all components of the active suppression of the cellular link of the immune system and reduction of phagocyte activity of neutrophils.

Entities:  

Keywords:  BURNED PATIENTS; DISORDERS; IMMUNE SYSTEM; SEVERELY

Year:  2009        PMID: 21991166      PMCID: PMC3188142     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN: 1592-9558


  11 in total

Review 1.  The role of complement in inflammation and adaptive immunity.

Authors:  R Barrington; M Zhang; M Fischer; M C Carroll
Journal:  Immunol Rev       Date:  2001-04       Impact factor: 12.988

2.  CD4+CD25+ regulatory T cells control innate immune reactivity after injury.

Authors:  Thomas J Murphy; Niamh Ni Choileain; Yan Zang; John A Mannick; James A Lederer
Journal:  J Immunol       Date:  2005-03-01       Impact factor: 5.422

3.  Negative signaling contributes to T-cell anergy in trauma patients.

Authors:  Gautam Bandyopadhyay; Asit De; Krzysztof Laudanski; Fang Li; Christopher Lentz; Paul Bankey; Carol Miller-Graziano
Journal:  Crit Care Med       Date:  2007-03       Impact factor: 7.598

4.  Kinetics of humoral responsiveness in severe thermal injury.

Authors:  F T Rapaport; R J Bachvaroff
Journal:  Ann Surg       Date:  1976-07       Impact factor: 12.969

5.  Cutting edge: CD95 maintains effector T cell homeostasis in chronic immune activation.

Authors:  Ramon Arens; Paul A Baars; Margot Jak; Kiki Tesselaar; Martin van der Valk; Marinus H J van Oers; René A W van Lier
Journal:  J Immunol       Date:  2005-05-15       Impact factor: 5.422

6.  Exacerbation of intestinal permeability in rats after a two-hit injury: burn and Enterococcus faecalis infection.

Authors:  Victoria A Samonte; Masakatsu Goto; Thyyar M Ravindranath; Nadeem Fazal; Vallie M Holloway; Amit Goyal; Richard L Gamelli; Mohammed M Sayeed
Journal:  Crit Care Med       Date:  2004-11       Impact factor: 7.598

7.  Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells.

Authors:  Kevin W Tinsley; Mitchell H Grayson; Paul E Swanson; Anne M Drewry; Katherine C Chang; Irene E Karl; Richard S Hotchkiss
Journal:  J Immunol       Date:  2003-07-15       Impact factor: 5.422

8.  Immunological and microbiological investigations of patients with burn injuries.

Authors:  Yordanka D Stoilova; Irina A Haidushkal; Mariana A Murdjeval; Ivan Z Traikov; Tatyana A Popova; Ani K Kevorkyan
Journal:  Folia Med (Plovdiv)       Date:  2007

9.  Mechanisms of postburn intestinal barrier dysfunction in the rat: roles of epithelial cell renewal, E-cadherin, and neutrophil extravasation.

Authors:  Walid M Al-Ghoul; Mehdi Khan; Nadeem Fazal; Mohammed M Sayeed
Journal:  Crit Care Med       Date:  2004-08       Impact factor: 7.598

10.  Mitogenic effects of purified outer membrane proteins from Pseudomonas aeruginosa.

Authors:  Y H Chen; R E Hancock; R I Mishell
Journal:  Infect Immun       Date:  1980-04       Impact factor: 3.441

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  3 in total

1.  Divergent and dynamic activity of endogenous retroviruses in burn patients and their inflammatory potential.

Authors:  Kang-Hoon Lee; HyungChul Rah; Tajia Green; Young-Kwan Lee; Debora Lim; Jean Nemzek; Wendy Wahl; David Greenhalgh; Kiho Cho
Journal:  Exp Mol Pathol       Date:  2014-02-06       Impact factor: 3.362

2.  Increased oxidative phosphorylation in lymphocytes does not atone for decreased cell numbers after burn injury.

Authors:  Tony Chao; Belinda I Gomez; Tiffany C Heard; Michael A Dubick; David M Burmeister
Journal:  Innate Immun       Date:  2020-01-06       Impact factor: 2.680

Review 3.  NLRP3 Inflammasome in Inflammation and Metabolism: Identifying Novel Roles in Postburn Adipose Dysfunction.

Authors:  Roohi Vinaik; Dalia Barayan; Marc G Jeschke
Journal:  Endocrinology       Date:  2020-09-01       Impact factor: 4.736

  3 in total

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