Literature DB >> 2199095

Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study.

J Delabie1, C de Wolf-Peeters, J J van den Oord, V J Desmet.   

Abstract

MRP14 and MRP8 are well-characterized calcium-binding proteins present in myeloid cells and mononuclear phagocytes. These antigens can easily be visualized in paraffin-embedded tissue, making use of monospecific polyclonal antibodies. This study evaluates MRP14 and MRP8 expression in mononuclear phagocytes in various granulomatous conditions. MRP14 is strongly expressed in all granulomatous conditions. MRP8 is variably expressed. Mononuclear phagocytes in granulomas of foreign body type, cat-scratch disease and erythema nodosum strongly express MRP8. In contrast, MRP8 expression is weak or absent in mononuclear phagocytes of sarcoidosis and tuberculosis. These results show differences in immunophenotype between non-phagocytic mononuclear phagocytes in delayed hypersensitivity type granulomas and phagocytic mononuclear phagocytes in non-hypersensitivity and non-immunological granulomas.

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Year:  1990        PMID： 2199095      PMCID： PMC1535019          DOI： 10.1111/j.1365-2249.1990.tb05301.x

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  16 in total

1.  KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.

Authors:  K A Pulford; E M Rigney; K J Micklem; M Jones; W P Stross; K C Gatter; D Y Mason
Journal:  J Clin Pathol       Date:  1989-04       Impact factor: 3.411

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Journal:  J Pathol       Date:  1969-05       Impact factor: 7.996

3.  Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors:  S M Hsu; L Raine; H Fanger
Journal:  J Histochem Cytochem       Date:  1981-04       Impact factor: 2.479

4.  Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis.

Authors:  K Odink; N Cerletti; J Brüggen; R G Clerc; L Tarcsay; G Zwadlo; G Gerhards; R Schlegel; C Sorg
Journal:  Nature       Date:  1987 Nov 5-11       Impact factor: 49.962

5.  Identification of tissue histiocytes on paraffin sections by a new monoclonal antibody.

Authors:  D J Flavell; D B Jones; D H Wright
Journal:  J Histochem Cytochem       Date:  1987-11       Impact factor: 2.479

6.  Cat scratch disease: a bacterial infection.

Authors:  D J Wear; A M Margileth; T L Hadfield; G W Fischer; C J Schlagel; F M King
Journal:  Science       Date:  1983-09-30       Impact factor: 47.728

Review 7.  A functional classification of granulomatous inflammation.

Authors:  K S Warren
Journal:  Ann N Y Acad Sci       Date:  1976       Impact factor: 5.691

8.  Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.

Authors:  T E Adams; J G Bodmer; W F Bodmer
Journal:  Immunology       Date:  1983-12       Impact factor: 7.397

Review 9.  The role of T cell--macrophage interactions in tuberculosis.

Authors:  S H Kaufmann; I E Flesch
Journal:  Springer Semin Immunopathol       Date:  1988

10.  Nodules on the legs. A clinical, histological and immunohistological study of 82 patients representing different types of nodular panniculitis.

Authors:  K M Niemi; L Förström; M Hannuksela; K K Mustakallio; O P Salo
Journal:  Acta Derm Venereol       Date:  1977       Impact factor: 4.437
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  17 in total

1.  Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex.

Authors:  Sharof Tugizov; Jennifer Berline; Rossana Herrera; Maria Elena Penaranda; Mayumi Nakagawa; Joel Palefsky
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

Review 2.  Functional and clinical aspects of the myelomonocyte protein calprotectin.

Authors:  B Johne; M K Fagerhol; T Lyberg; H Prydz; P Brandtzaeg; C F Naess-Andresen; I Dale
Journal:  Mol Pathol       Date:  1997-06

3.  Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 detected by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry.

Authors:  T Vogl; J Roth; C Sorg; F Hillenkamp; K Strupat
Journal:  J Am Soc Mass Spectrom       Date:  1999-11       Impact factor: 3.109

4.  An immunohistochemical analysis of onchocercal nodules: evidence for an interaction between macrophage MRP8/MRP14 and adult Onchocerca volvulus.

Authors:  J D Edgeworth; A Abiose; B R Jones
Journal:  Clin Exp Immunol       Date:  1993-04       Impact factor: 4.330

5.  A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent Tuberculosis Infection.

Authors:  Elliott D Crouser; Peter White; Evelyn Guirado Caceres; Mark W Julian; Audrey C Papp; Landon W Locke; Wolfgang Sadee; Larry S Schlesinger
Journal:  Am J Respir Cell Mol Biol       Date:  2017-10       Impact factor: 6.914

6.  MRP14 is elevated in the bronchoalveolar lavage fluid of fibrosing interstitial lung diseases.

Authors:  N M Korthagen; M M Nagtegaal; C H M van Moorsel; K M Kazemier; J M M van den Bosch; J C Grutters
Journal:  Clin Exp Immunol       Date:  2010-06-09       Impact factor: 4.330

7.  Increase of calcium levels in epithelial cells induces translocation of calcium-binding proteins migration inhibitory factor-related protein 8 (MRP8) and MRP14 to keratin intermediate filaments.

Authors:  M Goebeler; J Roth; C van den Bos; G Ader; C Sorg
Journal:  Biochem J       Date:  1995-07-15       Impact factor: 3.857

8.  Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid).

Authors:  E S Kleinerman; A K Raymond; C D Bucana; N Jaffe; M B Harris; I H Krakoff; R Benjamin; I J Fidler
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

9.  Immunophenotypic analysis of histiocytes involved in AIDS-associated Mycobacterium scrofulaceum infection: similarities with lepromatous lepra.

Authors:  J Delabie; C De Wolf-Peeters; H Bobbaers; G Bilbe; V J Desmet
Journal:  Clin Exp Immunol       Date:  1991-08       Impact factor: 4.330

10.  Different patterns of macrophage infiltration into allogeneic-murine and xenogeneic-human neoplasms growing in nude mice.

Authors:  C D Bucana; A Fabra; R Sanchez; I J Fidler
Journal:  Am J Pathol       Date:  1992-11       Impact factor: 4.307
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