Literature DB >> 21989608

Is screening effective in detecting untreated psychiatric disorders among newly diagnosed breast cancer patients?

Steven C Palmer1, Alison Taggi, Angela Demichele, James C Coyne.   

Abstract

BACKGROUND: A key purpose of routine distress screening is to ensure that cancer patients receive appropriate mental health care. Most studies validating screening instruments overestimate the effectiveness of screening by not differentiating between patients with untreated disorders and patients who are already being treated. This study adopts the novel strategy of evaluating the effectiveness of screening after correcting for disorder for which treatment is already being provided.
METHODS: A total of 437 recently diagnosed breast cancer patients received in-clinic distress screening and telephone-based psychiatric interviews. Analyses were conducted using receipt of psychotropic medication for mental health difficulties in the context of a psychiatric disorder as a proxy for identification and treatment.
RESULTS: Rates of elevated distress (33%), major depressive disorder (8%), minor depression (6%), dysthymia (2%), or generalized anxiety disorder (3%) were similar to those in other samples. Thirty-six percent of patients received psychotropic medication around the time of cancer diagnosis, including 64% of those with a current psychiatric diagnosis. Although 39% of patients with elevated distress had a psychiatric disorder, the positive predictive value of screening fell to 15% for an untreated psychiatric disorder and 6% had untreated depression.
CONCLUSION: Given the high rates of existing treatment, screening may not be efficient for identifying untreated disorder. Almost two-thirds of patients with treated disorders remain symptomatic. Use of symptom scales might reasonably be expanded to surveillance of treatment response or ruling out disorder. Substantial resources would likely be required to coordinate or manage psychiatric care among patients, as would a willingness to intervene in existing relationships with other providers.
Copyright © 2011 American Cancer Society.

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Year:  2011        PMID: 21989608      PMCID: PMC3421028          DOI: 10.1002/cncr.26603

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  61 in total

1.  Treatment adequacy for anxiety and depressive disorders in six European countries.

Authors:  A Fernández; J M Haro; M Martinez-Alonso; K Demyttenaere; T S Brugha; J Autonell; G de Girolamo; S Bernert; J P Lépine; J Alonso
Journal:  Br J Psychiatry       Date:  2007-02       Impact factor: 9.319

2.  The NCCN guideline for distress management: a case for making distress the sixth vital sign.

Authors:  Jimmie C Holland; Barry D Bultz
Journal:  J Natl Compr Canc Netw       Date:  2007-01       Impact factor: 11.908

Review 3.  Mood disorders in the medically ill: scientific review and recommendations.

Authors:  Dwight L Evans; Dennis S Charney; Lydia Lewis; Robert N Golden; Jack M Gorman; K Ranga Rama Krishnan; Charles B Nemeroff; J Douglas Bremner; Robert M Carney; James C Coyne; Mahlon R Delong; Nancy Frasure-Smith; Alexander H Glassman; Philip W Gold; Igor Grant; Lisa Gwyther; Gail Ironson; Robert L Johnson; Andres M Kanner; Wayne J Katon; Peter G Kaufmann; Francis J Keefe; Terence Ketter; Thomas P Laughren; Jane Leserman; Constantine G Lyketsos; William M McDonald; Bruce S McEwen; Andrew H Miller; Dominique Musselman; Christopher O'Connor; John M Petitto; Bruce G Pollock; Robert G Robinson; Steven P Roose; Julia Rowland; Yvette Sheline; David S Sheps; Gregory Simon; David Spiegel; Albert Stunkard; Trey Sunderland; Paul Tibbits; William J Valvo
Journal:  Biol Psychiatry       Date:  2005-08-01       Impact factor: 13.382

4.  Implementation of NCCN distress management guidelines by member institutions.

Authors:  Paul B Jacobsen; Sean Ransom
Journal:  J Natl Compr Canc Netw       Date:  2007-01       Impact factor: 11.908

5.  Management of depression for people with cancer (SMaRT oncology 1): a randomised trial.

Authors:  Vanessa Strong; Rachel Waters; Carina Hibberd; Gordon Murray; Lucy Wall; Jane Walker; Gillian McHugh; Andrew Walker; Michael Sharpe
Journal:  Lancet       Date:  2008-07-05       Impact factor: 79.321

6.  Performance of the Hospital Anxiety and Depression Scale as a screening tool for major depressive disorder in cancer patients.

Authors:  Jane Walker; Kirstine Postma; Gillian S McHugh; Robert Rush; Brian Coyle; Vanessa Strong; Michael Sharpe
Journal:  J Psychosom Res       Date:  2007-07       Impact factor: 3.006

7.  National patterns in antidepressant treatment by psychiatrists and general medical providers: results from the national comorbidity survey replication.

Authors:  Ramin Mojtabai; Mark Olfson
Journal:  J Clin Psychiatry       Date:  2008-07       Impact factor: 4.384

8.  Pooled results from 38 analyses of the accuracy of distress thermometer and other ultra-short methods of detecting cancer-related mood disorders.

Authors:  Alex J Mitchell
Journal:  J Clin Oncol       Date:  2007-09-10       Impact factor: 44.544

Review 9.  Risk of bias from inclusion of patients who already have diagnosis of or are undergoing treatment for depression in diagnostic accuracy studies of screening tools for depression: systematic review.

Authors:  Brett D Thombs; Erin Arthurs; Ghassan El-Baalbaki; Anna Meijer; Roy C Ziegelstein; Russell J Steele
Journal:  BMJ       Date:  2011-08-18

10.  Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis.

Authors:  A J Mitchell
Journal:  Br J Cancer       Date:  2008-05-27       Impact factor: 7.640

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  5 in total

1.  Prevalence and correlates of sexual morbidity in long-term breast cancer survivors.

Authors:  Greer A Raggio; Meghan L Butryn; Danielle Arigo; Renee Mikorski; Steven C Palmer
Journal:  Psychol Health       Date:  2014-01-28

2.  Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors.

Authors:  Shelli Kesler; Michelle Janelsins; Della Koovakkattu; Oxana Palesh; Karen Mustian; Gary Morrow; Firdaus S Dhabhar
Journal:  Brain Behav Immun       Date:  2012-06-12       Impact factor: 7.217

Review 3.  Effects of screening for psychological distress on patient outcomes in cancer: a systematic review.

Authors:  Anna Meijer; Michelle Roseman; Vanessa C Delisle; Katherine Milette; Brooke Levis; Achyuth Syamchandra; Michael E Stefanek; Donna E Stewart; Peter de Jonge; James C Coyne; Brett D Thombs
Journal:  J Psychosom Res       Date:  2013-02-27       Impact factor: 3.006

4.  The effects of a problem solving-based intervention on depressive symptoms and HIV medication adherence are independent.

Authors:  Robert Gross; Scarlett L Bellamy; Jennifer Chapman; Xiaoyan Han; Jacqueline O'Duor; Brian L Strom; Peter S Houts; Steven C Palmer; James C Coyne
Journal:  PLoS One       Date:  2014-01-06       Impact factor: 3.240

5.  Screening for psychological distress in follow-up care to identify head and neck cancer patients with untreated distress.

Authors:  Anne-Marie H Krebber; Femke Jansen; Pim Cuijpers; C René Leemans; Irma M Verdonck-de Leeuw
Journal:  Support Care Cancer       Date:  2015-12-23       Impact factor: 3.603

  5 in total

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