Literature DB >> 21988973

Networking for new drugs.

Claire Ainsworth.   

Abstract

Mesh：

Year:  2011        PMID： 21988973     DOI： 10.1038/nm1011-1166

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  6 in total

1.  Trial watch: phase III and submission failures: 2007-2010.

Authors:  John Arrowsmith
Journal:  Nat Rev Drug Discov       Date:  2011-02       Impact factor: 84.694

2.  Escherichia coli mutants lacking all possible combinations of eight penicillin binding proteins: viability, characteristics, and implications for peptidoglycan synthesis.

Authors:  S A Denome; P K Elf; T A Henderson; D E Nelson; K D Young
Journal:  J Bacteriol       Date:  1999-07       Impact factor: 3.490

3.  Genetics of gene expression and its effect on disease.

Authors:  Valur Emilsson; Gudmar Thorleifsson; Bin Zhang; Amy S Leonardson; Florian Zink; Jun Zhu; Sonia Carlson; Agnar Helgason; G Bragi Walters; Steinunn Gunnarsdottir; Magali Mouy; Valgerdur Steinthorsdottir; Gudrun H Eiriksdottir; Gyda Bjornsdottir; Inga Reynisdottir; Daniel Gudbjartsson; Anna Helgadottir; Aslaug Jonasdottir; Adalbjorg Jonasdottir; Unnur Styrkarsdottir; Solveig Gretarsdottir; Kristinn P Magnusson; Hreinn Stefansson; Ragnheidur Fossdal; Kristleifur Kristjansson; Hjortur G Gislason; Tryggvi Stefansson; Bjorn G Leifsson; Unnur Thorsteinsdottir; John R Lamb; Jeffrey R Gulcher; Marc L Reitman; Augustine Kong; Eric E Schadt; Kari Stefansson
Journal:  Nature       Date:  2008-03-16       Impact factor: 49.962

4.  Variations in DNA elucidate molecular networks that cause disease.

Authors:  Yanqing Chen; Jun Zhu; Pek Yee Lum; Xia Yang; Shirly Pinto; Douglas J MacNeil; Chunsheng Zhang; John Lamb; Stephen Edwards; Solveig K Sieberts; Amy Leonardson; Lawrence W Castellini; Susanna Wang; Marie-France Champy; Bin Zhang; Valur Emilsson; Sudheer Doss; Anatole Ghazalpour; Steve Horvath; Thomas A Drake; Aldons J Lusis; Eric E Schadt
Journal:  Nature       Date:  2008-03-16       Impact factor: 49.962

5.  The Mycobacterium tuberculosis drugome and its polypharmacological implications.

Authors:  Sarah L Kinnings; Li Xie; Kingston H Fung; Richard M Jackson; Lei Xie; Philip E Bourne
Journal:  PLoS Comput Biol       Date:  2010-11-04       Impact factor: 4.475

6.  Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir.

Authors:  Li Xie; Thomas Evangelidis; Lei Xie; Philip E Bourne
Journal:  PLoS Comput Biol       Date:  2011-04-28       Impact factor: 4.475
  6 in total
  11 in total

Review 1.  Diagnosing the decline in pharmaceutical R&D efficiency.

Authors:  Jack W Scannell; Alex Blanckley; Helen Boldon; Brian Warrington
Journal:  Nat Rev Drug Discov       Date:  2012-03-01       Impact factor: 84.694

Review 2.  New avenues for anti-epileptic drug discovery and development.

Authors:  Wolfgang Löscher; Henrik Klitgaard; Roy E Twyman; Dieter Schmidt
Journal:  Nat Rev Drug Discov       Date:  2013-09-20       Impact factor: 84.694

Review 3.  Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies.

Authors:  H Steve White; Wolfgang Löscher
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

4.  DISCOVERY OF MOLECULARLY TARGETED THERAPIES.

Authors:  Kelly Regan; Zachary Abrams; Michael Sharpnack; Arunima Srivastava; Kun Huang; Nigam Shah; Philip R O Payne
Journal:  Pac Symp Biocomput       Date:  2016

5.  Collaboration for rare disease drug discovery research.

Authors:  Nadia K Litterman; Michele Rhee; David C Swinney; Sean Ekins
Journal:  F1000Res       Date:  2014-10-31

6.  An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.

Authors:  Shahram Attarian; Jean-Michel Vallat; Laurent Magy; Benoît Funalot; Pierre-Marie Gonnaud; Arnaud Lacour; Yann Péréon; Odile Dubourg; Jean Pouget; Joëlle Micallef; Jérôme Franques; Marie-Noëlle Lefebvre; Karima Ghorab; Mahmoud Al-Moussawi; Vincent Tiffreau; Marguerite Preudhomme; Armelle Magot; Laurène Leclair-Visonneau; Tanya Stojkovic; Laura Bossi; Philippe Lehert; Walter Gilbert; Viviane Bertrand; Jonas Mandel; Aude Milet; Rodolphe Hajj; Lamia Boudiaf; Catherine Scart-Grès; Serguei Nabirotchkin; Mickael Guedj; Ilya Chumakov; Daniel Cohen
Journal:  Orphanet J Rare Dis       Date:  2014-12-18       Impact factor: 4.123

7.  Recommendations to enable drug development for inherited neuropathies: Charcot-Marie-Tooth and Giant Axonal Neuropathy.

Authors:  Lori Sames; Allison Moore; Renee Arnold; Sean Ekins
Journal:  F1000Res       Date:  2014-04-03

8.  Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy.

Authors:  Ilya Chumakov; Serguei Nabirotchkin; Nathalie Cholet; Aude Milet; Aurélie Boucard; Damien Toulorge; Yannick Pereira; Esther Graudens; Sory Traoré; Julie Foucquier; Mickael Guedj; Emmanuel Vial; Noëlle Callizot; Rémy Steinschneider; Tangui Maurice; Viviane Bertrand; Catherine Scart-Grès; Rodolphe Hajj; Daniel Cohen
Journal:  Sci Rep       Date:  2015-01-08       Impact factor: 4.379

9.  The chemical interactome space between the human host and the genetically defined gut metabotypes.

Authors:  Ulrik Plesner Jacobsen; Henrik Bjørn Nielsen; Falk Hildebrand; Jeroen Raes; Thomas Sicheritz-Ponten; Irene Kouskoumvekaki; Gianni Panagiotou
Journal:  ISME J       Date:  2012-11-22       Impact factor: 10.302

10.  VNP: Interactive Visual Network Pharmacology of Diseases, Targets, and Drugs.

Authors:  Q-N Hu; Z Deng; W Tu; X Yang; Z-B Meng; Z-X Deng; J Liu
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2014-03-12
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