Literature DB >> 21988240

Mechanism of activation and inactivation of Gq/phospholipase C-β signaling nodes.

T Kendall Harden1, Gary L Waldo, Stephanie N Hicks, John Sondek.   

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Year:  2011        PMID: 21988240      PMCID: PMC3626114          DOI: 10.1021/cr200209p

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  122 in total

1.  A unique fold of phospholipase C-beta mediates dimerization and interaction with G alpha q.

Authors:  Alex U Singer; Gary L Waldo; T Kendall Harden; John Sondek
Journal:  Nat Struct Biol       Date:  2002-01

Review 2.  Inositol phospholipids and cell surface receptor function.

Authors:  R H Michell
Journal:  Biochim Biophys Acta       Date:  1975-03-25

Review 3.  Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?

Authors:  Guillaume Drin; Suzanne Scarlata
Journal:  Cell Signal       Date:  2007-04-29       Impact factor: 4.315

Review 4.  Inositol trisphosphate and diacylglycerol: two interacting second messengers.

Authors:  M J Berridge
Journal:  Annu Rev Biochem       Date:  1987       Impact factor: 23.643

5.  Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.

Authors:  C K Chen; M E Burns; W He; T G Wensel; D A Baylor; M I Simon
Journal:  Nature       Date:  2000-02-03       Impact factor: 49.962

Review 6.  Regulation of phospholipase C isozymes by ras superfamily GTPases.

Authors:  T Kendall Harden; John Sondek
Journal:  Annu Rev Pharmacol Toxicol       Date:  2006       Impact factor: 13.820

7.  Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation.

Authors:  Simona Citro; Sundeep Malik; Emily A Oestreich; Julie Radeff-Huang; Grant G Kelley; Alan V Smrcka; Joan Heller Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-18       Impact factor: 11.205

8.  Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity.

Authors:  J W Lomasney; H F Cheng; L P Wang; Y Kuan; S Liu; S W Fesik; K King
Journal:  J Biol Chem       Date:  1996-10-11       Impact factor: 5.157

Review 9.  PIP2 is a necessary cofactor for ion channel function: how and why?

Authors:  Byung-Chang Suh; Bertil Hille
Journal:  Annu Rev Biophys       Date:  2008       Impact factor: 12.981

10.  Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain.

Authors:  K M Ferguson; M A Lemmon; J Schlessinger; P B Sigler
Journal:  Cell       Date:  1995-12-15       Impact factor: 41.582

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  18 in total

Review 1.  Role of phospholipase Cε in physiological phosphoinositide signaling networks.

Authors:  Alan V Smrcka; Joan Heller Brown; George G Holz
Journal:  Cell Signal       Date:  2012-01-20       Impact factor: 4.315

2.  Potent and Selective Peptide-based Inhibition of the G Protein Gαq.

Authors:  Thomas H Charpentier; Gary L Waldo; Emily G Lowery-Gionta; Krzysztof Krajewski; Brian D Strahl; Thomas L Kash; T Kendall Harden; John Sondek
Journal:  J Biol Chem       Date:  2016-10-14       Impact factor: 5.157

3.  M3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency.

Authors:  Wei Kan; Merel Adjobo-Hermans; Michael Burroughs; Guy Faibis; Sundeep Malik; Gregory G Tall; Alan V Smrcka
Journal:  J Biol Chem       Date:  2014-03-04       Impact factor: 5.157

Review 4.  Targeting G protein-coupled receptor signalling by blocking G proteins.

Authors:  Adrian P Campbell; Alan V Smrcka
Journal:  Nat Rev Drug Discov       Date:  2018-09-28       Impact factor: 84.694

Review 5.  Chemical modulation of glycerolipid signaling and metabolic pathways.

Authors:  Sarah A Scott; Thomas P Mathews; Pavlina T Ivanova; Craig W Lindsley; H Alex Brown
Journal:  Biochim Biophys Acta       Date:  2014-01-15

6.  The binding of activated Gαq to phospholipase C-β exhibits anomalous affinity.

Authors:  Punya Navaratnarajah; Anne Gershenson; Elliott M Ross
Journal:  J Biol Chem       Date:  2017-08-24       Impact factor: 5.157

7.  Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.

Authors:  Xiaoyang Wang; Matthew Barrett; John Sondek; T Kendall Harden; Qisheng Zhang
Journal:  Biochemistry       Date:  2012-06-22       Impact factor: 3.162

8.  Activation of Phospholipase C β by Gβγ and Gαq Involves C-Terminal Rearrangement to Release Autoinhibition.

Authors:  Isaac J Fisher; Meredith L Jenkins; Gregory G Tall; John E Burke; Alan V Smrcka
Journal:  Structure       Date:  2020-05-12       Impact factor: 5.006

9.  G protein βγ subunits directly interact with and activate phospholipase Cϵ.

Authors:  Jerry C Madukwe; Elisabeth E Garland-Kuntz; Angeline M Lyon; Alan V Smrcka
Journal:  J Biol Chem       Date:  2018-03-13       Impact factor: 5.157

10.  Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis.

Authors:  Leonid E Fridlyand; Louis H Philipson
Journal:  PLoS One       Date:  2016-05-03       Impact factor: 3.240

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