Literature DB >> 21987110

Is nitric oxide a hormone?

Asghar Ghasemi1, Saleh Zahediasl1.   

Abstract

Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production in tissues, it is stabilized and transported as nitrite and/or S-nitrosothiols in the blood to target cells.

Entities:  

Keywords:  Endocrine; Hormone; Nitric oxide; Nitrate; Nitrite

Mesh:

Substances:

Year:  2011        PMID: 21987110      PMCID: PMC3639748     

Source DB:  PubMed          Journal:  Iran Biomed J        ISSN: 1028-852X


  104 in total

1.  Evidence for in vivo transport of bioactive nitric oxide in human plasma.

Authors:  Tienush Rassaf; Michael Preik; Petra Kleinbongard; Thomas Lauer; Christian Heiss; Bodo-Eckehard Strauer; Martin Feelisch; Malte Kelm
Journal:  J Clin Invest       Date:  2002-05       Impact factor: 14.808

2.  Influence of sex and age on serum nitrite/nitrate concentration in healthy subjects.

Authors:  T Watanabe; M Akishita; K Toba; K Kozaki; M Eto; N Sugimoto; T Kiuchi; M Hashimoto; W Shirakawa; Y Ouchi
Journal:  Clin Chim Acta       Date:  2000-11       Impact factor: 3.786

3.  Smoking status-dependent association of the 27-bp repeat polymorphism in intron 4 of endothelial nitric oxide synthase gene with plasma nitric oxide concentrations.

Authors:  Suin Yoon; Jesung Moon; Chol Shin; Eunkyung Kim; Sangmee Ahn Jo; Inho Jo
Journal:  Clin Chim Acta       Date:  2002-10       Impact factor: 3.786

4.  Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice.

Authors:  Mattias Carlström; Filip J Larsen; Thomas Nyström; Michael Hezel; Sara Borniquel; Eddie Weitzberg; Jon O Lundberg
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-27       Impact factor: 11.205

Review 5.  NO to obesity: does nitric oxide regulate fat oxidation and insulin sensitivity?

Authors:  Hans-Georg Joost; Matthias H Tschöp
Journal:  Endocrinology       Date:  2007-10       Impact factor: 4.736

6.  Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain.

Authors:  J Garthwaite; S L Charles; R Chess-Williams
Journal:  Nature       Date:  1988-11-24       Impact factor: 49.962

7.  Nitric oxide synthase activity in mitochondria.

Authors:  P Ghafourifar; C Richter
Journal:  FEBS Lett       Date:  1997-12-01       Impact factor: 4.124

8.  Serum concentrations of nitric oxide, tumor necrosis factor (TNF)-alpha and TNF soluble receptors in women with overweight and obesity.

Authors:  Magdalena Olszanecka-Glinianowicz; Barbara Zahorska-Markiewicz; Joanna Janowska; Aleksander Zurakowski
Journal:  Metabolism       Date:  2004-10       Impact factor: 8.694

9.  Serum nitric oxide metabolites in subjects with metabolic syndrome.

Authors:  Saleh Zahedi Asl; Asghar Ghasemi; Fereidoun Azizi
Journal:  Clin Biochem       Date:  2008-09-03       Impact factor: 3.281

10.  The relationship among serum cytokines, chemokine, nitric oxide, and leptin in children with type 1 diabetes mellitus.

Authors:  Hui-Chen Lo; Su-Chen Lin; Yu-Mei Wang
Journal:  Clin Biochem       Date:  2004-08       Impact factor: 3.281

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  14 in total

Review 1.  Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension.

Authors:  Sevda Gheibi; Sajad Jeddi; Khosrow Kashfi; Asghar Ghasemi
Journal:  Biochem Pharmacol       Date:  2018-01-09       Impact factor: 5.858

Review 2.  Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes.

Authors:  Sevda Gheibi; Alan P Samsonov; Shahsanam Gheibi; Alexandra B Vazquez; Khosrow Kashfi
Journal:  Biochem Pharmacol       Date:  2020-01-21       Impact factor: 5.858

3.  Effect of nitrate and L-arginine therapy on nitric oxide levels in serum, heart, and aorta of fetal hypothyroid rats.

Authors:  Asghar Ghasemi; Fatemeh Mehrazin; Saleh Zahediasl
Journal:  J Physiol Biochem       Date:  2013-04-09       Impact factor: 4.158

4.  Potential therapeutic effects of nitrate/nitrite and type 2 diabetes mellitus.

Authors:  Asghar Ghasemi; Saleh Zahediasl
Journal:  Int J Endocrinol Metab       Date:  2013-04-01

5.  Comparison of inducible nitric oxide synthase activity in pancreatic islets of young and aged rats.

Authors:  Khadije Farrokhfall; Mehri Seyed Hashtroudi; Asghar Ghasemi; Hossein Mehrani
Journal:  Iran J Basic Med Sci       Date:  2015-02       Impact factor: 2.699

6.  Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications.

Authors:  Zahra Bahadoran; Asghar Ghasemi; Parvin Mirmiran; Fereidoun Azizi; Farzad Hadaegh
Journal:  Nutr Metab (Lond)       Date:  2015-05-16       Impact factor: 4.169

7.  Dietary L-arginine intake and the incidence of coronary heart disease: Tehran lipid and glucose study.

Authors:  Zahra Bahadoran; Parvin Mirmiran; Zhaleh Tahmasebinejad; Fereidoun Azizi
Journal:  Nutr Metab (Lond)       Date:  2016-03-15       Impact factor: 4.169

Review 8.  Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention.

Authors:  Yanling Wu; Yanping Ding; Yoshimasa Tanaka; Wen Zhang
Journal:  Int J Med Sci       Date:  2014-09-06       Impact factor: 3.738

9.  The Association of Dietary l-Arginine Intake and Serum Nitric Oxide Metabolites in Adults: A Population-Based Study.

Authors:  Parvin Mirmiran; Zahra Bahadoran; Asghar Ghasemi; Fereidoun Azizi
Journal:  Nutrients       Date:  2016-05-20       Impact factor: 5.717

10.  Dietary L-Arginine Intakes and the Risk of Metabolic Syndrome: A 6-Year Follow-Up in Tehran Lipid and Glucose Study.

Authors:  Parvin Mirmiran; Sajjad Khalili Moghadam; Zahra Bahadoran; Asghar Ghasemi; Fereidoun Azizi
Journal:  Prev Nutr Food Sci       Date:  2017-12-31
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