Literature DB >> 21986444

Achieving specificity in Akt signaling in cancer.

Alex Toker1.   

Abstract

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Year:  2012        PMID： 21986444      PMCID： PMC3614006          DOI： 10.1016/j.advenzreg.2011.09.020

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN： 2212-4926


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  80 in total

1.  Large-scale phosphorylation analysis of mouse liver.

Authors:  Judit Villén; Sean A Beausoleil; Scott A Gerber; Steven P Gygi
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-22       Impact factor: 11.205

2.  Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation.

Authors:  Takeshi Yoshizaki; Takeshi Imamura; Jennie L Babendure; Juu-Chin Lu; Noriyuki Sonoda; Jerrold M Olefsky
Journal:  Mol Cell Biol       Date:  2007-05-21       Impact factor: 4.272

3.  PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.

Authors:  John Brognard; Emma Sierecki; Tianyan Gao; Alexandra C Newton
Journal:  Mol Cell       Date:  2007-03-23       Impact factor: 17.970

Review 4.  The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer.

Authors:  R L Dillon; D E White; W J Muller
Journal:  Oncogene       Date:  2007-02-26       Impact factor: 9.867

5.  Akt1 governs breast cancer progression in vivo.

Authors:  Xiaoming Ju; Sanjay Katiyar; Chenguang Wang; Manran Liu; Xuanmao Jiao; Shengwen Li; Jie Zhou; Jacob Turner; Michael P Lisanti; Robert G Russell; Susette C Mueller; John Ojeifo; William S Chen; Nissim Hay; Richard G Pestell
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-25       Impact factor: 11.205

6.  Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Authors:  Arkaitz Carracedo; Li Ma; Julie Teruya-Feldstein; Federico Rojo; Leonardo Salmena; Andrea Alimonti; Ainara Egia; Atsuo T Sasaki; George Thomas; Sara C Kozma; Antonella Papa; Caterina Nardella; Lewis C Cantley; Jose Baselga; Pier Paolo Pandolfi
Journal:  J Clin Invest       Date:  2008-09       Impact factor: 14.808

7.  Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes.

Authors:  Yvonne Ng; Georg Ramm; Jamie A Lopez; David E James
Journal:  Cell Metab       Date:  2008-04       Impact factor: 27.287

8.  Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.

Authors:  Klarisa Rikova; Ailan Guo; Qingfu Zeng; Anthony Possemato; Jian Yu; Herbert Haack; Julie Nardone; Kimberly Lee; Cynthia Reeves; Yu Li; Yerong Hu; Zhiping Tan; Matthew Stokes; Laura Sullivan; Jeffrey Mitchell; Randy Wetzel; Joan Macneill; Jian Min Ren; Jin Yuan; Corey E Bakalarski; Judit Villen; Jon M Kornhauser; Bradley Smith; Daiqiang Li; Xinmin Zhou; Steven P Gygi; Ting-Lei Gu; Roberto D Polakiewicz; John Rush; Michael J Comb
Journal:  Cell       Date:  2007-12-14       Impact factor: 41.582

Review 9.  AKT/PKB signaling: navigating downstream.

Authors:  Brendan D Manning; Lewis C Cantley
Journal:  Cell       Date:  2007-06-29       Impact factor: 41.582

10.  A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.

Authors:  John D Carpten; Andrew L Faber; Candice Horn; Gregory P Donoho; Stephen L Briggs; Christiane M Robbins; Galen Hostetter; Sophie Boguslawski; Tracy Y Moses; Stephanie Savage; Mark Uhlik; Aimin Lin; Jian Du; Yue-Wei Qian; Douglas J Zeckner; Greg Tucker-Kellogg; Jeffrey Touchman; Ketan Patel; Spyro Mousses; Michael Bittner; Richard Schevitz; Mei-Huei T Lai; Kerry L Blanchard; James E Thomas
Journal:  Nature       Date:  2007-07-04       Impact factor: 69.504
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  27 in total

1.  Akt signaling dynamics in individual cells.

Authors:  Sean M Gross; Peter Rotwein
Journal:  J Cell Sci       Date:  2015-06-03       Impact factor: 5.285

2.  Role of PI3K/Akt on migration and invasion of MCF10A cells treated with extracellular vesicles from MDA-MB-231 cells stimulated with linoleic acid.

Authors:  Elizabeth Leal-Orta; Javier Ramirez-Ricardo; Pedro Cortes-Reynosa; Octavio Galindo-Hernandez; Eduardo Perez Salazar
Journal:  J Cell Commun Signal       Date:  2018-10-25       Impact factor: 5.782

3.  Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling.

Authors:  Inchul You; Emily C Erickson; Katherine A Donovan; Nicholas A Eleuteri; Eric S Fischer; Nathanael S Gray; Alex Toker
Journal:  Cell Chem Biol       Date:  2019-12-16       Impact factor: 8.116

4.  Suppressive effect of formononetin on platelet-derived growth factor-BB-stimulated proliferation and migration of vascular smooth muscle cells.

Authors:  Zhuo Chen; Suixin Liu; Ying Cai; Kangling Xie; Wenliang Zhang; Lei Dong; Yuan Liu; Fan Zheng; Yaoshan Dun; Ning Li
Journal:  Exp Ther Med       Date:  2016-07-13       Impact factor: 2.447

Review 5.  mTOR signaling in tumorigenesis.

Authors:  Kai Xu; Pengda Liu; Wenyi Wei
Journal:  Biochim Biophys Acta       Date:  2014-11-01

Review 6.  Signaling specificity in the Akt pathway in biology and disease.

Authors:  Alex Toker; Sandra Marmiroli
Journal:  Adv Biol Regul       Date:  2014-04-19

7.  Quantification of growth factor signaling and pathway cross talk by live-cell imaging.

Authors:  Sean M Gross; Peter Rotwein
Journal:  Am J Physiol Cell Physiol       Date:  2017-01-18       Impact factor: 4.249

8.  Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.

Authors:  Monica Y Lee; Amelia K Luciano; Eric Ackah; Juan Rodriguez-Vita; Tara A Bancroft; Anne Eichmann; Michael Simons; Themis R Kyriakides; Manuel Morales-Ruiz; William C Sessa
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-18       Impact factor: 11.205

9.  Enhanced phosphatidylinositol 3-kinase (PI3K)/Akt signaling has pleiotropic targets in hippocampal neurons exposed to iron-induced oxidative stress.

Authors:  Romina María Uranga; Sebastián Katz; Gabriela Alejandra Salvador
Journal:  J Biol Chem       Date:  2013-05-16       Impact factor: 5.157

Review 10.  Phosphatidylinositolphosphate phosphatase activities and cancer.

Authors:  Simon A Rudge; Michael J O Wakelam
Journal:  J Lipid Res       Date:  2015-08-24       Impact factor: 5.922
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