Literature DB >> 21985759

Does light alcohol consumption during pregnancy improve offspring's cognitive development?

Wenbin Liang1, Tanya Chikritzhs.   

Abstract

We posit that: (i) light alcohol consumption during pregnancy does not improve the cognitive development of human offspring and (ii) observational study outcomes indicating apparent protective effects arise from residual confounding due to socioeconomic status. Our hypotheses counter emerging hypotheses apparent in the epidemiological literature that light alcohol consumption during pregnancy improves offspring's cognitive development. Determining the plausibility of this proposition is important given its potential to influence women's alcohol consumption behavior during pregnancy. However, given ethical concerns, it is unlikely that a randomized control trial will be conducted to test this hypothesis. The veracity of alcohol's purported positive effect on cognitive development is therefore explored here by comparing research evidence on light alcohol consumption to the evidence for folate and DHA supplementation intake during pregnancy. An alternative approach for further testing this hypothesis in observational studies is also suggested.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21985759     DOI: 10.1016/j.mehy.2011.09.043

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  7 in total

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2.  Alcohol consumption and health status of family members: health impacts without ingestion.

Authors:  W Liang; T Chikritzhs
Journal:  Intern Med J       Date:  2013-09       Impact factor: 2.048

3.  Inconsistency in reporting abstention and heavy drinking frequency: associations with sex and socioeconomic status, and potential impacts.

Authors:  Robyn M Kydd; Jennie Connor
Journal:  Alcohol Alcohol       Date:  2015-02-03       Impact factor: 2.826

4.  Examining the Relationship between Heavy Alcohol Use and Assaults: With Adjustment for the Effects of Unmeasured Confounders.

Authors:  Wenbin Liang; Tanya Chikritzhs
Journal:  Biomed Res Int       Date:  2015-08-25       Impact factor: 3.411

5.  Observational research on alcohol use and chronic disease outcome: new approaches to counter biases.

Authors:  Wenbin Liang; Tanya Chikritzhs
Journal:  ScientificWorldJournal       Date:  2013-07-09

6.  An investigation of the significance of residual confounding effect.

Authors:  Wenbin Liang; Yuejen Zhao; Andy H Lee
Journal:  Biomed Res Int       Date:  2014-02-17       Impact factor: 3.411

7.  A proxy outcome approach for causal effect in observational studies: a simulation study.

Authors:  Wenbin Liang; Yuejen Zhao; Andy H Lee
Journal:  Biomed Res Int       Date:  2014-02-18       Impact factor: 3.411

  7 in total

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