Literature DB >> 21985003

Regulation through degradation.

Allison Doerr.   

Abstract

Two groups present small molecule–induced degradation systems for controlling protein function in living systems.

Year:  2011        PMID： 21985003     DOI： 10.1038/nmeth.1686

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  2 in total

1.  Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

Authors:  Taavi K Neklesa; Hyun Seop Tae; Ashley R Schneekloth; Michael J Stulberg; Timothy W Corson; Thomas B Sundberg; Kanak Raina; Scott A Holley; Craig M Crews
Journal:  Nat Chem Biol       Date:  2011-07-03       Impact factor: 15.040

2.  Small-molecule displacement of a cryptic degron causes conditional protein degradation.

Authors:  Kimberly M Bonger; Ling-chun Chen; Corey W Liu; Thomas J Wandless
Journal:  Nat Chem Biol       Date:  2011-07-03       Impact factor: 15.040
  2 in total
  1 in total

1.  Up-regulation of TREK-2 potassium channels in cultured astrocytes requires de novo protein synthesis: relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia.

Authors:  Aixa F Rivera-Pagán; David E Rivera-Aponte; Katya V Melnik-Martínez; Astrid Zayas-Santiago; Lilia Y Kucheryavykh; Antonio H Martins; Luis A Cubano; Serguei N Skatchkov; Misty J Eaton
Journal:  PLoS One       Date:  2015-04-17       Impact factor: 3.240
  1 in total

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