| Literature DB >> 21984662 |
Stéfani Cibele Rossi1, Manuela Dreyer da Silva, Laercio Dante Stein Piancini, Ciro Alberto Oliveira Ribeiro, Marta Margarete Cestari, Helena Cristina Silva de Assis.
Abstract
The study evaluated the sublethal effects of the herbicides glyphosate (Roundup) and diuron (Hexaron) and the mixture of them, used extremely in agriculture, through biomarkers in fish. The glutathione S-transferase activity increased (74%) and catalase activity decreased (37%) at the higher exposure concentration of Hexaron in comparison to the control group, suggesting an activation of this metabolism route. Membrane damage was observed at the higher exposure of Roundup and in the mixture group compared to the control group, which can be related to the nuclear alterations observed in these exposed groups. The cholinesterase activity was also inhibited (37%) in mixture group compared to the control group and no gill morphology damage was found. The results suggested a potential synergic effect in some analysed parameters.Entities:
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Year: 2011 PMID： 21984662 DOI： 10.1007/s00128-011-0397-6
Source DB: PubMed Journal: Bull Environ Contam Toxicol ISSN： 0007-4861 Impact factor: 2.151