Literature DB >> 21983557

PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy.

Alberto M Martelli1, Giovanna Tabellini, Francesca Ricci, Camilla Evangelisti, Francesca Chiarini, Roberta Bortul, James A McCubrey, Francesco Antonio Manzoli.   

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Year:  2012        PMID： 21983557     DOI： 10.1016/j.advenzreg.2011.09.019

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN： 2212-4926


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  8 in total

1.  Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.

Authors:  William H Chappell; Stephen L Abrams; Richard A Franklin; Michelle M LaHair; Giuseppe Montalto; Melchiorre Cervello; Alberto M Martelli; Ferdinando Nicoletti; Saverio Candido; Massimo Libra; Jerry Polesel; Renato Talamini; Michele Milella; Agostino Tafuri; Linda S Steelman; James A McCubrey
Journal:  Cell Cycle       Date:  2012-11-16       Impact factor: 4.534

2.  Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia.

Authors:  Antonino Maria Spartà; Daniela Bressanin; Francesca Chiarini; Annalisa Lonetti; Alessandra Cappellini; Cecilia Evangelisti; Camilla Evangelisti; Fraia Melchionda; Andrea Pession; Alice Bertaina; Franco Locatelli; James A McCubrey; Alberto M Martelli
Journal:  Cell Cycle       Date:  2014-05-29       Impact factor: 4.534

3.  Interleukin (IL)-7 Signaling in the Tumor Microenvironment.

Authors:  Iwona Bednarz-Misa; Mariusz A Bromke; Małgorzata Krzystek-Korpacka
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

4.  Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature.

Authors:  Salvatore Serravalle; Salvatore N Bertuccio; Annalisa Astolfi; Fraia Melchionda; Andrea Pession
Journal:  Biomed Res Int       Date:  2016-11-27       Impact factor: 3.411

5.  Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway.

Authors:  Annalisa Lonetti; Alessandra Cappellini; Alice Bertaina; Franco Locatelli; Andrea Pession; Francesca Buontempo; Camilla Evangelisti; Cecilia Evangelisti; Ester Orsini; Laura Zambonin; Luca Maria Neri; Alberto Maria Martelli; Francesca Chiarini
Journal:  J Hematol Oncol       Date:  2016-10-24       Impact factor: 17.388

6.  Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway.

Authors:  Yanfei Jia; Yan Qi; Yunshan Wang; Xiaoli Ma; Yihui Xu; Jun Wang; Xiaoqian Zhang; Meihua Gao; Beibei Cong; Shuyi Han
Journal:  Cancer Cell Int       Date:  2019-01-08       Impact factor: 5.722

7.  Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling.

Authors:  Theresa Lowinus; Florian H Heidel; Tanima Bose; Subbaiah Chary Nimmagadda; Tina Schnöder; Clemens Cammann; Ingo Schmitz; Ulrike Seifert; Thomas Fischer; Burkhart Schraven; Ursula Bommhardt
Journal:  Cell Commun Signal       Date:  2019-01-16       Impact factor: 5.712

Review 8.  Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.

Authors:  James A McCubrey; Linda S Steelman; William H Chappell; Stephen L Abrams; Giuseppe Montalto; Melchiorre Cervello; Ferdinando Nicoletti; Paolo Fagone; Grazia Malaponte; Maria C Mazzarino; Saverio Candido; Massimo Libra; Jörg Bäsecke; Sanja Mijatovic; Danijela Maksimovic-Ivanic; Michele Milella; Agostino Tafuri; Lucio Cocco; Camilla Evangelisti; Francesca Chiarini; Alberto M Martelli
Journal:  Oncotarget       Date:  2012-09
  8 in total

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