Literature DB >> 21981908

New(s) to the (Z-)ring.

Clare L Kirkpatrick1, Patrick H Viollier.   

Abstract

Cytokinesis in bacteria is mediated by a macromolecular machine known as the divisome, consisting of an assembly of FtsZ polymers around the cylindrical axis of the cell and the downstream regulators of division that are subsequently recruited to it. FtsZ polymerizes into filaments in a GTP-dependent manner, similarly to its eukaryotic structural homolog tubulin. The initial placement of the FtsZ polymerization site is tightly regulated by multiple mechanisms, as are the subsequent polymer reshaping and force generation that separate the two daughter cells from each other. New factors have been recently discovered that contribute to this regulation, notably affecting FtsZ polymer shaping, and modulating FtsZ polymerization in response to the metabolic or redox state of the cell.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21981908     DOI: 10.1016/j.mib.2011.09.011

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN: 1369-5274            Impact factor:   7.934


  24 in total

1.  β-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus.

Authors:  Edgar Ferrer-González; Malvika Kaul; Ajit K Parhi; Edmond J LaVoie; Daniel S Pilch
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

2.  A conserved coiled-coil protein pair focuses the cytokinetic Z-ring in Caulobacter crescentus.

Authors:  Selamawit Abi Woldemeskel; Ryan McQuillen; Alex M Hessel; Jie Xiao; Erin D Goley
Journal:  Mol Microbiol       Date:  2017-07-03       Impact factor: 3.501

3.  Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus.

Authors:  Malvika Kaul; Lilly Mark; Ajit K Parhi; Edmond J LaVoie; Daniel S Pilch
Journal:  Antimicrob Agents Chemother       Date:  2016-06-20       Impact factor: 5.191

4.  Crystallization and preliminary X-ray crystallographic analysis of Z-ring-associated protein (ZapD) from Escherichia coli.

Authors:  Sang Hyeon Son; Hyung Ho Lee
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-01-28       Impact factor: 1.056

5.  Enterococcal and streptococcal resistance to PC190723 and related compounds: molecular insights from a FtsZ mutational analysis.

Authors:  Malvika Kaul; Yongzheng Zhang; Ajit K Parhi; Edmond J Lavoie; Steve Tuske; Eddy Arnold; John E Kerrigan; Daniel S Pilch
Journal:  Biochimie       Date:  2013-06-25       Impact factor: 4.079

Review 6.  Divided we stand: splitting synthetic cells for their proliferation.

Authors:  Yaron Caspi; Cees Dekker
Journal:  Syst Synth Biol       Date:  2014-05-27

7.  Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ.

Authors:  Maria A Schumacher; Wenjie Zeng
Journal:  Proc Natl Acad Sci U S A       Date:  2016-04-18       Impact factor: 11.205

8.  An FtsZ-targeting prodrug with oral antistaphylococcal efficacy in vivo.

Authors:  Malvika Kaul; Lilly Mark; Yongzheng Zhang; Ajit K Parhi; Edmond J Lavoie; Daniel S Pilch
Journal:  Antimicrob Agents Chemother       Date:  2013-09-16       Impact factor: 5.191

Review 9.  FtsZ ring stability: of bundles, tubules, crosslinks, and curves.

Authors:  Kuo-Hsiang Huang; Jorge Durand-Heredia; Anuradha Janakiraman
Journal:  J Bacteriol       Date:  2013-03-01       Impact factor: 3.490

Review 10.  Building complexity: insights into self-organized assembly of microtubule-based architectures.

Authors:  Radhika Subramanian; Tarun M Kapoor
Journal:  Dev Cell       Date:  2012-11-13       Impact factor: 12.270

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