Increasing adherence for latent tuberculosis infection therapy with health department-administered therapy.

Therapy is almost universally recommended for children with latent tuberculosis infection, but long courses of therapy can decrease adherence to drug therapy. The only variable positively associated with adherence to latent tuberculosis infection therapy in our population was health department-assisted administration of drugs (odds ratio, 7.2; 95% confidence interval, 3.8-13.8).