Literature DB >> 2197960

The transforming growth factor-betas. A new family of immunoregulatory molecules.

M A Palladino1, R E Morris, H F Starnes, A D Levinson.   

Abstract

Within the past three years there has been a rapid expansion in our knowledge of the role TGF-beta mediates in regulating immune responses in vitro. Whether the TGF-beta will be clinically useful to suppress immune responses to transplanted organs or autoimmune responses is unknown. However, now that highly purified quantities of TGF-beta are available through recombinant DNA technologies, questions concerning the in vivo immunosuppressive activities of TGF-beta can be answered.

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Year:  1990        PMID： 2197960     DOI： 10.1111/j.1749-6632.1990.tb16110.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  18 in total

1.  Effect of FK 506 on FK-binding protein and transforming growth factor beta gene expression.

Authors:  P Rao; H Sun; J Snyder; J J Fung; T E Starzl
Journal:  Transplant Proc       Date:  1991-12       Impact factor: 1.066

2.  Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis : a therapeutic study using a macrophage-deactivating compound.

Authors:  K Palmblad; H Erlandsson-Harris; K J Tracey; U Andersson
Journal:  Am J Pathol       Date:  2001-02       Impact factor: 4.307

3.  Transforming growth factor-beta 1 (TGF-beta1) expression in ovine lentivirus-induced lymphoid interstitial pneumonia.

Authors:  B Moreno; C J Woodall; N J Watt; G D Harkiss
Journal:  Clin Exp Immunol       Date:  1998-04       Impact factor: 4.330

4.  Inhibitory RNA molecules in immunotherapy for cancer.

Authors:  Chih-Ping Mao; T-C Wu
Journal:  Methods Mol Biol       Date:  2010

5.  Lymphocytes infiltrating colorectal cancer have low proliferative capacity but can secrete normal levels of interferon gamma.

Authors:  W J Bateman; I Donnellan; I A Fraser; L S Wong; A G Morris
Journal:  Cancer Immunol Immunother       Date:  1995-07       Impact factor: 6.968

6.  Local cytokine response in Helicobacter pylori-infected subjects.

Authors:  C Lindholm; M Quiding-Järbrink; H Lönroth; A Hamlet; A M Svennerholm
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

7.  Inhibitory effects of Helicobacter pylori infection on murine autoimmune gastritis.

Authors:  M Ohana; K Okazaki; C Oshima; K Kawasaki; T Fukui; H Tamaki; M Matsuura; M Asada; T Nishi; K Uchida; S Uose; H Nakase; M Iwano; Y Matsushima; H Hiai; T Chiba
Journal:  Gut       Date:  2003-08       Impact factor: 23.059

8.  Effects of transforming growth factor-beta on murine astrocyte glutamine synthetase activity. Implications in neuronal injury.

Authors:  C C Chao; S Hu; M Tsang; J Weatherbee; T W Molitor; W R Anderson; P K Peterson
Journal:  J Clin Invest       Date:  1992-11       Impact factor: 14.808

9.  Transforming growth factor-beta-mediated down-regulation of antitumor cytotoxicity of spleen cells from MOPC-315 tumor-bearing mice engaged in tumor eradication following low-dose melphalan therapy.

Authors:  L M Weiskirch; Y Bar-Dagan; M B Mokyr
Journal:  Cancer Immunol Immunother       Date:  1994-04       Impact factor: 6.968

10.  A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance.

Authors:  R Josien; P Douillard; C Guillot; M Müschen; I Anegon; J Chetritt; S Menoret; C Vignes; J P Soulillou; M C Cuturi
Journal:  J Clin Invest       Date:  1998-12-01       Impact factor: 14.808
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