Literature DB >> 21978147

Disparities between prescribing of secondary prevention therapies for stroke and coronary artery disease in general practice.

Emma Heeley1, Craig Anderson, Anushka Patel, Alan Cass, David Peiris, Andrew Weekes, John Chalmers.   

Abstract

BACKGROUND: Extensive evidence exists regarding the effectiveness of secondary prevention measures in patients with cardiovascular disease. AIM: We aimed to examine the management and risk perceptions of cardiovascular events in people with established cardiovascular disease.
METHODS: We analyzed data on 1453 patients, ≥55 year old, with a history of cardiovascular disease, from the Australian Hypertension and Absolute Risk Study.
RESULTS: Compared with those 533 patients with stroke/transient ischemic attack, the 743 patients with coronary artery disease were twice as likely to have been prescribed secondary prevention therapies even after adjustment for potential confounding variables (adjusted relative risks 1·85; 95% confidence interval 1·56-2·19, 42% vs. 73% for use of the combination of blood pressure-lowering, lipid-lowering and antiplatelet therapies) and to have better control of lipid and blood pressure levels. General practitioners estimated that only 27% of patients with stroke/transient ischemic attack - 38% of those with coronary artery disease and 41% of those with both conditions - were at a high risk (≥15%) of a recurrent event. Patients similarly underestimated their risk of recurrent cardiovascular events, with only 8% of stroke/transient ischemic attack, 11% of coronary and 15% of combination disease patients rating themselves at 'high' or 'very-high' risk.
CONCLUSIONS: This study reaffirms the large treatment gap in the uptake of secondary prevention for cardiovascular disease in primary care settings, being much greater for patients with cerebral compared with cardiac cardiovascular disease. This appears to be related to differential perceptions of cardiovascular risk across different vascular territories in both patients and doctors.
© 2011 The Authors. International Journal of Stroke © 2011 World Stroke Organization.

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Year:  2011        PMID: 21978147     DOI: 10.1111/j.1747-4949.2011.00613.x

Source DB:  PubMed          Journal:  Int J Stroke        ISSN: 1747-4930            Impact factor:   5.266


  7 in total

1.  Medicines taken by older Australians after transient ischaemic attack or ischaemic stroke: a retrospective database study.

Authors:  Janet K Sluggett; Gillian E Caughey; Michael B Ward; Andrew L Gilbert
Journal:  Int J Clin Pharm       Date:  2015-04-29

2.  Using Classification and Regression Trees (CART) to Identify Prescribing Thresholds for Cardiovascular Disease.

Authors:  Chris Schilling; Duncan Mortimer; Kim Dalziel; Emma Heeley; John Chalmers; Philip Clarke
Journal:  Pharmacoeconomics       Date:  2016-02       Impact factor: 4.981

3.  GPs' perspectives on secondary cardiovascular prevention in older age: a focus group study in the Netherlands.

Authors:  Petra G van Peet; Yvonne M Drewes; Jacobijn Gussekloo; Wouter de Ruijter
Journal:  Br J Gen Pract       Date:  2015-11       Impact factor: 5.386

4.  Determinants for achieving the LDL-C target of lipid control for secondary prevention of cardiovascular events in Taiwan.

Authors:  Li-Ting Ho; Wei-Hsian Yin; Shao-Yuan Chuang; Wei-Kung Tseng; Yen-Wen Wu; I-Chang Hsieh; Tsung-Hsien Lin; Yi-Heng Li; Lien-Chi Huang; Kuo-Yang Wang; Kwo-Chang Ueng; Ching-Chang Fang; Wen-Harn Pan; Hung-I Yeh; Chau-Chung Wu; Jaw-Wen Chen
Journal:  PLoS One       Date:  2015-03-10       Impact factor: 3.240

5.  Use of generic and essential medicines for prevention and treatment of cardiovascular diseases in Portugal.

Authors:  Helena Gama; Carla Torre; José Pedro Guerreiro; Ana Azevedo; Suzete Costa; Nuno Lunet
Journal:  BMC Health Serv Res       Date:  2017-06-29       Impact factor: 2.655

6.  [Compliance with recommendations in secondary prevention of stroke in primary care].

Authors:  Carmen Tamayo-Ojeda; Neus Parellada-Esquius; Betlem Salvador-González; Pilar Ángeles Oriol-Torón; M Dolores Rodríguez-Garrido; Dolores Muñoz-Segura
Journal:  Aten Primaria       Date:  2017-04-07       Impact factor: 1.137

Review 7.  Personalized medicine and stroke prevention: where are we?

Authors:  Joosup Kim; Amanda G Thrift; Mark R Nelson; Christopher F Bladin; Dominique A Cadilhac
Journal:  Vasc Health Risk Manag       Date:  2015-12-02
  7 in total

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