Literature DB >> 21978069

A virtual source model for kilo-voltage cone beam CT: source characteristics and model validation.

E Spezi1, W Volken, D Frei, M K Fix.   

Abstract

PURPOSE: The purpose of this investigation was to study the source characteristics of a clinical kilo-voltage cone beam CT unit and to develop and validate a virtual source model that could be used for treatment planning purposes.
METHODS: We used a previously commissioned full Monte Carlo model and new bespoke software to study the source characteristics of a clinical kilo-voltage cone beam CT (CBCT) unit. We identified the main particle sources, their spatial, energy and angular distribution for all the image acquisition presets currently used in our clinical practice. This includes a combination of two energies (100 and 120 kVp), two filters (neutral and bowtie), and eight different x-ray beam apertures. We subsequently built a virtual source model which we validated against full Monte Carlo calculations.
RESULTS: We found that the radiation output of the clinical kilo-voltage cone beam CT unit investigated in this study could be reproduced with a virtual model comprising of two sources (target and filtration cone) or three sources (target, filtration cone and bowtie filter) when additional filtration was used. With this model, we accounted for more than 97% of the photons exiting the unit. Each source in our model was characterised by a origin distribution in both X and Y directions, a fluence map, a single energy spectrum for unfiltered beams and a two dimensional energy spectrum for bowtie filtered beams. The percentage dose difference between full Monte Carlo and virtual source model based dose distributions was well within the statistical uncertainty associated with the calculations ( ± 2%, one standard deviation) in all cases studied.
CONCLUSIONS: The virtual source that we developed is accurate in calculating the dose delivered from a commercial kilo-voltage cone beam CT unit operating with routine clinical image acquisition settings. Our data have also shown that target, filtration cone, and bowtie filter sources needed to be all included in the model in order to accurately replicate the dose distribution from the clinical radiation beam.

Mesh:

Year:  2011        PMID: 21978069     DOI: 10.1118/1.3626574

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  A measurement-based generalized source model for Monte Carlo dose simulations of CT scans.

Authors:  Xin Ming; Yuanming Feng; Ransheng Liu; Chengwen Yang; Li Zhou; Hezheng Zhai; Jun Deng
Journal:  Phys Med Biol       Date:  2017-01-12       Impact factor: 3.609

2.  Commissioning kilovoltage cone-beam CT beams in a radiation therapy treatment planning system.

Authors:  Parham Alaei; Emiliano Spezi
Journal:  J Appl Clin Med Phys       Date:  2012-11-08       Impact factor: 2.102

3.  A single-source photon source model of a linear accelerator for Monte Carlo dose calculation.

Authors:  Obioma Nwankwo; Gerhard Glatting; Frederik Wenz; Jens Fleckenstein
Journal:  PLoS One       Date:  2017-09-08       Impact factor: 3.240

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.