Literature DB >> 21972588

[Boron neutron capture therapy (BNCT) as cancer treatment].

Heikki Joensuu1, Leena Kankaanranta, Mikko Tenhunen, Kauko Saarilahti.   

Abstract

Boron neutron capture therapy leads to a strong local radiotherapy effect. The efficacy of the method in cancer therapy requires sufficient accumulation of boron into and a fairly superficial location of the tumor. The efficacy and tolerability of this therapy has been investigated in Finland especially in locally recurring head and neck cancer. These tumors have responded favorably to boron neutron capture therapy and the treatment has been relatively well tolerated, although most cancers have recurred locally with few cases of durable complete remission.

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Mesh:

Year:  2011        PMID: 21972588

Source DB:  PubMed          Journal:  Duodecim        ISSN: 0012-7183


  2 in total

1.  In vitro studies of DNA damage and repair mechanisms induced by BNCT in a poorly differentiated thyroid carcinoma cell line.

Authors:  C Rodriguez; M Carpano; P Curotto; S Thorp; M Casal; G Juvenal; M Pisarev; M A Dagrosa
Journal:  Radiat Environ Biophys       Date:  2018-02-16       Impact factor: 1.925

2.  Improvement of the boron neutron capture therapy (BNCT) by the previous administration of the histone deacetylase inhibitor sodium butyrate for the treatment of thyroid carcinoma.

Authors:  M Perona; C Rodríguez; M Carpano; L Thomasz; S Nievas; M Olivera; S Thorp; P Curotto; E Pozzi; S Kahl; M Pisarev; G Juvenal; A Dagrosa
Journal:  Radiat Environ Biophys       Date:  2013-05-01       Impact factor: 1.925

  2 in total

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