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Literature DB >> 21971179

The HIF-1α-c-Myc pathway and tumorigenesis: evading the apoptotic gate-keeper.

Nicole Fer¹, Giovanni Melillo.

Abstract

Entities: Gene

Mesh：

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Year: 2011 PMID： 21971179 PMCID： PMC3356795 DOI： 10.4161/cc.10.19.17049

Source DB: PubMed Journal: Cell Cycle ISSN： 1551-4005 Impact factor: 4.534

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8 in total

Review 1. HIF-1: a target for cancer, ischemia and inflammation--too good to be true?

Authors: Giovanni Melillo
Journal: Cell Cycle Date: 2004-02 Impact factor: 4.534

2. Requirement of evading apoptosis for HIF-1α-induced malignant progression in mouse cells.

Authors: Masami Hayashi; Yoo Young-Gun Yoo; Jared Christensen; L Eric Huang
Journal: Cell Cycle Date: 2011-07-15 Impact factor: 4.534

3. HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

Authors: Minori Koshiji; Kenneth K-W To; Stefanie Hammer; Kensuke Kumamoto; Adrian L Harris; Paul Modrich; L Eric Huang
Journal: Mol Cell Date: 2005-03-18 Impact factor: 17.970

4. HIF-1α confers aggressive malignant traits on human tumor cells independent of its canonical transcriptional function.

Authors: Young-Gun Yoo; Jared Christensen; L Eric Huang
Journal: Cancer Res Date: 2011-02-08 Impact factor: 12.701

5. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours.

Authors: T G Graeber; C Osmanian; T Jacks; D E Housman; C J Koch; S W Lowe; A J Giaccia
Journal: Nature Date: 1996-01-04 Impact factor: 49.962

Review 6. The interplay between MYC and HIF in cancer.

Authors: Chi V Dang; Jung-whan Kim; Ping Gao; Jason Yustein
Journal: Nat Rev Cancer Date: 2008-01 Impact factor: 60.716

Review 7. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics.

Authors: G L Semenza
Journal: Oncogene Date: 2009-11-30 Impact factor: 9.867

8. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Authors: John D Gordan; Jessica A Bertout; Cheng-Jun Hu; J Alan Diehl; M Celeste Simon
Journal: Cancer Cell Date: 2007-04 Impact factor: 31.743

8 in total

6 in total

1. C-myc overexpression drives melanoma metastasis by promoting vasculogenic mimicry via c-myc/snail/Bax signaling.

Authors: Xian Lin; Ran Sun; Xiulan Zhao; Dongwang Zhu; Xueming Zhao; Qiang Gu; Xueyi Dong; Danfang Zhang; Yanhui Zhang; Yanlei Li; Baocun Sun
Journal: J Mol Med (Berl) Date: 2016-08-19 Impact factor: 4.599

2. The "Sharp" blade against HIF-mediated metastasis.

Authors: Ivano Amelio; Gerry Melino
Journal: Cell Cycle Date: 2012-11-27 Impact factor: 4.534

3. Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.

Authors: Chao Zhang; Chunzhang Yang; Michael J Feldman; Herui Wang; Ying Pang; Dominic M Maggio; Dongwang Zhu; Cody L Nesvick; Pauline Dmitriev; Petra Bullova; Prashant Chittiboina; Roscoe O Brady; Karel Pacak; Zhengping Zhuang
Journal: Oncotarget Date: 2017-05-23