Literature DB >> 21970295

Photoinduced DNA cleavage promoted by two copper(II) complexes of tetracyclines and 1,10-phenanthroline.

Tiago Bortolotto1, Priscila Pereira Silva, Ademir Neves, Elene Cristina Pereira-Maia, Hernán Terenzi.   

Abstract

In this report, we demonstrate how UV-light exposure can enhance DNA cleavage promoted by two copper(II) complexes of tetracyclines and 1,10-phenanthroline about 40 times in comparison to nonirradiated conditions. In addition, new aspects regarding their DNA binding properties, as well as the mechanism of the cleavage reaction, were also investigated.
© 2011 American Chemical Society

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Year:  2011        PMID： 21970295     DOI： 10.1021/ic201349s

Source DB:  PubMed          Journal:  Inorg Chem        ISSN： 0020-1669            Impact factor:   5.165


  3 in total

1.  New Heteroleptic Ruthenium(II) Complexes with Sulfamethoxypyridazine and Diimines as Potential Antitumor Agents.

Authors:  Ariane C C de Melo; Jaime M S V P Santana; Kelen J R C Nunes; Bernardo L Rodrigues; Nathalia Castilho; Philipe Gabriel; Adolfo H Moraes; Mayra de A Marques; Guilherme A P de Oliveira; Ívina P de Souza; Hernán Terenzi; Elene C Pereira-Maia
Journal:  Molecules       Date:  2019-06-07       Impact factor: 4.411

2.  Peroxoniobium inhibits leukemia cell growth.

Authors:  Elene C Pereira-Maia; Ivina P Souza; Kelen J R C Nunes; Alexandre A Castro; Teodorico C Ramalho; Fernando Steffler; Helio A Duarte; Ana Pacheli; Poliana Chagas; Luiz C A Oliveira
Journal:  RSC Adv       Date:  2018-03-14       Impact factor: 3.361

Review 3.  Classification Framework and Chemical Biology of Tetracycline-Structure-Based Drugs.

Authors:  Domenico Fuoco
Journal:  Antibiotics (Basel)       Date:  2012-06-12
  3 in total

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