Literature DB >> 21968651

PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone.

Ching-Wen Lou1, Chun-Hsu Yao, Yueh-Sheng Chen, Chao-Tsang Lu, Wen-Cheng Chen, Ke-Chung Yen, Jia-Horng Lin.   

Abstract

Poly(lactic acid) (PLA) twisted yarn was braided into a 6-layered, hollow, cylindrical braid on a 16-spindle braid machine. The PLA braid was then placed inside a β-TCP tube, forming the PLA/β-TCP complex tube which imitates the porous structure of sponge bone. Different components and structures were studied to determine the best bone molding material. The β-TCP tube was created by sintering TCP powder mixed with stearic acid in a ratio of 1:1.5 to form a highly porous and well-structured tube with interconnected pores; its resulting porosity was 85.8 ± 0.93%. The PLA/β-TCP complex tube was implanted in a rabbit's femur and after 3 months a marrow cavity was discovered at the tube's core. New bone was also observed, regenerating around the PLA braid within the PLA/β-TCP complex tube.

Entities:  

Keywords:  16-spindle braid machine; MG-63; complex tubes; poly(lactic acid); β-TCP

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Year:  2012        PMID: 21968651     DOI: 10.1163/092050611X597762

Source DB:  PubMed          Journal:  J Biomater Sci Polym Ed        ISSN: 0920-5063            Impact factor:   3.517


  2 in total

1.  Comparison and preparation of multilayered polylactic acid fabric strengthen calcium phosphate-based bone substitutes for orthopedic applications.

Authors:  Wen-Cheng Chen; Chia-Ling Ko; Jia-Kai Yang; Hui-Yu Wu; Jia-Horng Lin
Journal:  J Artif Organs       Date:  2015-08-18       Impact factor: 1.731

2.  Effect of Different Manufacturing Methods on the Conflict between Porosity and Mechanical Properties of Spiral and Porous Polyethylene Terephthalate/Sodium Alginate Bone Scaffolds.

Authors:  Ching-Wen Lou; Chien-Lin Huang; Chih-Kuang Chen; Chi-Fan Liu; Shih-Peng Wen; Jia-Horng Lin
Journal:  Materials (Basel)       Date:  2015-12-14       Impact factor: 3.623

  2 in total

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