Literature DB >> 21965428

Impact of the French campaign to reduce inappropriate ambulatory antibiotic use on the prescription and consultation rates for respiratory tract infections.

Pierre Chahwakilian1, Benedikt Huttner, Benoit Schlemmer, Stephan Harbarth.   

Abstract

OBJECTIVES: To assess long-term trends in the volume of ambulatory antibiotic prescriptions and prescription and consultation rates for respiratory tract infections (RTIs) in France in relation to the yearly public antibiotic campaign since 2002.
METHODS: Data collected on representative cohorts of office-based physicians and pharmacies in France participating in IMS Health panels between 1980 and 2009 were analysed retrospectively. Main outcome measures were antibiotic prescriptions per 1000 inhabitants per year (PIY), consultations per 1000 inhabitants per year and proportion of consultations resulting in antibiotic prescriptions.
RESULTS: The peak in ambulatory antibiotic prescriptions occurred in 1997 (1468 PIY). Although prescriptions had decreased by 6% until 2001, prescriptions fell sharply (-22%) between 2001 and 2004, followed by stable prescription rates until 2009. The 2001-09 decrease in antibiotic prescriptions was driven by a sharp decline in office-based antibiotic prescriptions (-33%), exclusively achieved through a decrease in prescriptions for RTIs. Consultations for RTIs steadily declined between 2001 and 2009 (-23%), with the proportion of consultations resulting in antibiotic prescriptions decreasing from 58% to 46%. Not all types of RTIs were equally affected. The largest decrease in prescriptions was observed for nasopharyngitis and influenza. Rates for bronchitis, sinusitis, otitis media and tonsillitis remained persistently high.
CONCLUSIONS: During its first 3 years, the French public campaign accelerated a pre-existing decrease in ambulatory antibiotic prescriptions. The decrease in consultation rates suggests that altered illness behaviour of patients may have contributed to the observed decline. The persistently high prescribing rates for certain RTIs show that further effort is needed to improve antibiotic prescribing in France.

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Year:  2011        PMID: 21965428     DOI: 10.1093/jac/dkr387

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  18 in total

1.  Assessing the impact of national antibiotic campaigns in Europe.

Authors:  M Filippini; L G González Ortiz; G Masiero
Journal:  Eur J Health Econ       Date:  2012-06-17

2.  Factors associated with the use of rapid antigen diagnostic tests in children presenting with acute pharyngitis among French general practitioners.

Authors:  A Michel-Lepage; B Ventelou; P Verger; C Pulcini
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-10-31       Impact factor: 3.267

3.  Evaluation of effects of an operational multidisciplinary team on antibiotic use in the medium to long term at a French university hospital.

Authors:  Béatrice Demoré; Pauline Humbert; Emmanuelle Boschetti; Sibylle Bevilacqua; Isabelle Clerc-Urmès; Thierry May; Céline Pulcini; Nathalie Thilly
Journal:  Int J Clin Pharm       Date:  2017-07-29

Review 4.  Metrics for evaluating antibiotic use and prescribing in outpatient settings.

Authors:  Valerie Leung; Bradley J Langford; Rita Ha; Kevin L Schwartz
Journal:  JAC Antimicrob Resist       Date:  2021-07-19

5.  Approaching the quality of antibiotic prescriptions in primary care using reimbursement data.

Authors:  C Pulcini; C Lions; B Ventelou; P Verger
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-09-16       Impact factor: 3.267

6.  Appropriate international measures for outpatient antibiotic prescribing and consumption: recommendations from a national data comparison of different measures.

Authors:  Samuel Coenen; Birgit Gielen; Adriaan Blommaert; Philippe Beutels; Niel Hens; Herman Goossens
Journal:  J Antimicrob Chemother       Date:  2013-10-01       Impact factor: 5.790

7.  Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat.

Authors:  Jérémie F Cohen; Jean-Yves Pauchard; Nils Hjelm; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2020-06-04

Review 8.  How to educate prescribers in antimicrobial stewardship practices.

Authors:  Céline Pulcini; Inge C Gyssens
Journal:  Virulence       Date:  2013-01-29       Impact factor: 5.882

9.  Identification of cultural determinants of antibiotic use cited in primary care in Europe: a mixed research synthesis study of integrated design "Culture is all around us".

Authors:  Pia Touboul-Lundgren; Siri Jensen; Johann Drai; Morten Lindbæk
Journal:  BMC Public Health       Date:  2015-09-17       Impact factor: 3.295

10.  Cross-sectional survey: risk-averse French GPs use more rapid-antigen diagnostic tests in tonsillitis in children.

Authors:  Audrey Michel-Lepage; Bruno Ventelou; Antoine Nebout; Pierre Verger; Céline Pulcini
Journal:  BMJ Open       Date:  2013-10-25       Impact factor: 2.692

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