| Literature DB >> 2196459 |
P P Hung1, P K Chanda, R J Natuk, B B Mason, M Chengalvala, B M Bhat, K L Molnar-Kimber, S K Dheer, J E Morin, S Mizutani.
Abstract
Types 4 and 7 adenovirus are currently used as live, oral vaccines for the prevention of adenovirus respiratory disease in military recruits. These vaccine strains have been genetically engineered in order to express HIV-1 or HBV antigens in infected cells. A dog model was developed to evaluate the immunogenicity of these recombinant vaccines. Dogs inoculated with live adenovirus-HBV recombinant vaccine produced antibody against hepatitis B surface antigen.Entities:
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Year: 1990 PMID： 2196459
Source DB: PubMed Journal: Nat Immun Cell Growth Regul ISSN： 0254-7600