| Literature DB >> 21964290 |
Massimiliano Agostini1, Paola Tucci, Gerry Melino.
Abstract
Apoptosis, a genetically regulated form of cell death with distinct biochemical and morphological features, plays a relevant physiological and pathological role in the organism, being pivotal in the maintenance of tissue development and homeostasis in the adult as well as in the regulation of immune responses. Deregulation of this process causes several human disorders including cancer, autoimmune and neurodegenerative diseases. Thus, modulation of the apoptotic process and of cell death in general, is a potential therapeutic approach for the treatment of several human pathologies.Entities:
Mesh:
Year: 2011 PMID: 21964290 DOI: 10.1016/j.bbrc.2011.09.081
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575